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Red face may be a specific sign of SARS-CoV-2 alpha variant #MMPMID34230877
Nakaya A; Ogura E; Katayama Y; Yoshii M; Yoshino E; Hozumi K; Tago S; Teranishi Y; Minamibashi Y; Harada M; Yoshioka M; Kawano Y; Arai Y; Yoshida K; Shimizu S; Ogura K; Iwashita K
IDCases 2021[]; 25 (ä): e01214 PMID34230877show ga
Japan is currently suffering the fourth wave of the COVID-19 pandemic, with the dominant type being SARS-CoV-2 alpha variant. Patients with COVID-19 variant types show more aggressive symptoms. In the present study, three patients developed a red face during treatment. Two of them suddenly worsened shortly after. We assumed that the red face reflected a cytokine storm and conjectured that it may be a specific sign of variant type COVID-19, because we have never seen it in patients with non-variant type. Moreover, we believe that red face may be predictive of a sudden deterioration.