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10.1172/jci.insight.150909 http://scihub22266oqcxt.onion/10.1172/jci.insight.150909 34228642!8492306!34228642     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34228642&cmd=llinks): Failed to open stream: HTTP request failed! 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Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents |pdf=|usr=}}{{34228642}} gab.com Text Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents JO: JCI Insight http://www.kidney.de/pget.php?&tw=1&pmid=34228642 #FOAvip As SARS-CoV-2 continues to spread globally, questions have emerged regarding the strength and durability of immune responses in specific populations. In this study, we evaluated humoral immune responses in 69 children and adolescents with asymptomatic or mild symptomatic SARS-CoV-2 infection. We detected robust IgM, IgG, and IgA antibody responses to a broad array of SARS-CoV-2 antigens at the time of acute infection and 2 and 4 months after acute infection in all participants. Notably, these antibody responses were associated with virus-neutralizing activity that was still detectable 4 months after acute infection in 94% of children. Moreover, antibody responses and neutralizing activity in sera from children and adolescents were comparable or superior to those observed in sera from 24 adults with mild symptomatic infection. Taken together, these findings indicate that children and adolescents with mild or asymptomatic SARS-CoV-2 infection generate robust and durable humoral immune responses that can likely contribute to protection from reinfection. Twit Text FOAVip Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents ????JCI Insight http://www.kidney.de/pget.php?&tw=1&pmid=34228642 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34228642 #FOAvip English Wikipedia <ref>{{Cite pmid|34228642}}</ref> Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents #MMPMID34228642 Garrido C; Hurst JH; Lorang CG; Aquino JN; Rodriguez J; Pfeiffer TS; Singh T; Semmes EC; Lugo DJ; Rotta AT; Turner NA; Burke TW; McClain MT; Petzold EA; Permar SR; Moody MA; Woods CW; Kelly MS; Fouda GG JCI Insight 2021[Sep]; 6 (17): ä PMID34228642show ga As SARS-CoV-2 continues to spread globally, questions have emerged regarding the strength and durability of immune responses in specific populations. In this study, we evaluated humoral immune responses in 69 children and adolescents with asymptomatic or mild symptomatic SARS-CoV-2 infection. We detected robust IgM, IgG, and IgA antibody responses to a broad array of SARS-CoV-2 antigens at the time of acute infection and 2 and 4 months after acute infection in all participants. Notably, these antibody responses were associated with virus-neutralizing activity that was still detectable 4 months after acute infection in 94% of children. Moreover, antibody responses and neutralizing activity in sera from children and adolescents were comparable or superior to those observed in sera from 24 adults with mild symptomatic infection. Taken together, these findings indicate that children and adolescents with mild or asymptomatic SARS-CoV-2 infection generate robust and durable humoral immune responses that can likely contribute to protection from reinfection. |Adolescent[MESH] |Antibodies, Neutralizing/*blood/immunology[MESH] |Antibodies, Viral/*blood/immunology[MESH] |Asymptomatic Diseases[MESH] |COVID-19/blood/*immunology/pathology[MESH] |Child[MESH] |Female[MESH] |Humans[MESH] |Male[MESH]Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable (epmc).pdf DeepDyve Pubget Overpricing