Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1007/s13258-021-01136-6 http://scihub22266oqcxt.onion/10.1007/s13258-021-01136-6 34228320!8258482!34228320     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+Genomics 2021 ; 43 (11): 1351-1359 Nephropedia Template TP {{tp|p=34228320|t=2021. Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV |pdf=|usr=}}{{34228320}} gab.com Text Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV JO: Genes Genomics http://www.kidney.de/pget.php?&tw=1&pmid=34228320 #FOAvip BACKGROUND: COVID-19, as a novel coronavirus disease caused by new coronavirus SARS-CoV-2, spreads all over the world, and brings harm to human in many countries. Humans suffered a lot from both SARS-CoV-2 now and by SARS-CoV in the year 2003. It is important to understand the differences and the relationships between these two types of viruses. OBJECTIVE: To compare relative synonymous codon usage of ORF1ab gene in SARS-CoV-2 and SARS-CoV, relative synonymous codon usage of their genomes are studied in this paper from the bioinformatics perspective. METHODS: The ORF1ab gene, which is an important non-structural polyprotein coding gene and now used for nucleic acid detection markers in many measurement method, in both SARS-CoV-2 (30 strains) and SARS-CoV (20 strains) are considered to be the research object in the present paper. The relative synonymous codon usage values of the ORF1ab gene are calculated to characterize the differences and the evolutionary characteristics among 50 strains. RESULTS: There is a significant difference between SARS-CoV and SARS-CoV-2 when the relative synonymous codon usage value of ORF1ab genes is concerned. The results suggest that codon usage pattern of SARS-CoV is more similar to human than that of the SARS-CoV-2, and that the inner difference in SARS-CoV-2 strains is larger than that of SARS-CoV, which denote the larger diversity exits in the SARS-CoV-2 virus. CONCLUSION: These results show that the relative synonymous codon usage values in the coronavirus could be used for further research on their evolutionary phenomenon. Twit Text FOAVip Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV ????Genes Genomics http://www.kidney.de/pget.php?&tw=1&pmid=34228320 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34228320 #FOAvip English Wikipedia <ref>{{Cite pmid|34228320}}</ref> Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV #MMPMID34228320 Li G; Zhang L; Du N Genes Genomics 2021[Nov]; 43 (11): 1351-1359 PMID34228320show ga BACKGROUND: COVID-19, as a novel coronavirus disease caused by new coronavirus SARS-CoV-2, spreads all over the world, and brings harm to human in many countries. Humans suffered a lot from both SARS-CoV-2 now and by SARS-CoV in the year 2003. It is important to understand the differences and the relationships between these two types of viruses. OBJECTIVE: To compare relative synonymous codon usage of ORF1ab gene in SARS-CoV-2 and SARS-CoV, relative synonymous codon usage of their genomes are studied in this paper from the bioinformatics perspective. METHODS: The ORF1ab gene, which is an important non-structural polyprotein coding gene and now used for nucleic acid detection markers in many measurement method, in both SARS-CoV-2 (30 strains) and SARS-CoV (20 strains) are considered to be the research object in the present paper. The relative synonymous codon usage values of the ORF1ab gene are calculated to characterize the differences and the evolutionary characteristics among 50 strains. RESULTS: There is a significant difference between SARS-CoV and SARS-CoV-2 when the relative synonymous codon usage value of ORF1ab genes is concerned. The results suggest that codon usage pattern of SARS-CoV is more similar to human than that of the SARS-CoV-2, and that the inner difference in SARS-CoV-2 strains is larger than that of SARS-CoV, which denote the larger diversity exits in the SARS-CoV-2 virus. CONCLUSION: These results show that the relative synonymous codon usage values in the coronavirus could be used for further research on their evolutionary phenomenon. |COVID-19[MESH] |Codon Usage/*genetics[MESH] |Computational Biology[MESH] |Evolution, Molecular[MESH] |Genome, Viral[MESH] |Humans[MESH] |Open Reading Frames[MESH] |Phylogeny[MESH] |Polyproteins/*genetics[MESH] |SARS-CoV-2/classification/*genetics[MESH] |Severe acute respiratory syndrome-related coronavirus/*genetics[MESH]Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV (epmc).pdf DeepDyve Pubget Overpricing