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suck abstract from ncbi


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pmid34227769      J+Assoc+Physicians+India 2021 ; 69 (1): 16-18
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  • Clinical Presentation of Cases with SARS-CoV-2 Reinfection/ Reactivation #MMPMID34227769
  • Mahajan NN; Gajbhiye RK; Lokhande PD; Bahirat S; Modi D; Mathe AM; Bharmal R; Rathi S; Mohite SC; Tilve A
  • J Assoc Physicians India 2021[Jan]; 69 (1): 16-18 PMID34227769show ga
  • BACKGROUND: Reinfection/reactivation of SARS-CoV-2 has been a matter of great interest from the immunological and vaccine perspective. However, little is known about the clinical presentation of such reinfection/reactivation. We report a case series of 9 COVID-19 patients having experienced two clinically- and/or virologically-confirmed episodes of COVID-19. METHODS: Epidemiological and clinical characteristics of 9 healthcare workers (HCWs) with two episodes of SARS-CoV-2 are described. RESULTS: The incidence of reinfection/reactivation amongst the HCWs was 2% (9 out of 491) with an average remission period of 66 days (range 43-78 days). Amongst the cases of reinfection 4/9 were asymptomatic in first episode were symptomatic in second episode. There is negative correlation between numbers of days the patients took to become SARS-CoV-2 negative by RT-CPR and/or clinically recover in the first episode and the second episode irrespective for the time spent in remission. CONCLUSION: Shorter durations of SARS-COV-2 infection in the first episode are associated with longer time to recovery in the second episode in patients with re-infection/reactivation.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Health Personnel[MESH]
  • |Humans[MESH]
  • |Reinfection[MESH]


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