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10.1007/s00018-021-03889-5 http://scihub22266oqcxt.onion/10.1007/s00018-021-03889-5 34223911!8256233!34223911     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34223911&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Mol+Life+Sci 2021 ; 78 (16): 5953-5976 Nephropedia Template TP {{tp|p=34223911|t=2021. Host factors facilitating SARS-CoV-2 virus infection and replication in the lungs |pdf=|usr=}}{{34223911}} gab.com Text Host factors facilitating SARS-CoV-2 virus infection and replication in the lungs JO: Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=34223911 #FOAvip SARS-CoV-2 is the virus causing the major pandemic facing the world today. Although, SARS-CoV-2 primarily causes lung infection, a variety of symptoms have proven a systemic impact on the body. SARS-CoV-2 has spread in the community quickly infecting humans from all age, ethnicities and gender. However, fatal outcomes have been linked to specific host factors and co-morbidities such as age, hypertension, immuno-deficiencies, chronic lung diseases or metabolic disorders. A major shift in the microbiome of patients suffering of the coronavirus disease 2019 (COVID-19) have also been observed and is linked to a worst outcome of the disease. As many co-morbidities are already known to be associated with a dysbiosis of the microbiome such as hypertension, diabetes and metabolic disorders. Host factors and microbiome changes are believed to be involved as a network in the acquisition of the infection and the development of the diseases. We will review in detail in this manuscript, the immune response toward SARS-CoV-2 infection as well as the host factors involved in the facilitation and worsening of the infection. We will also address the impact of COVID-19 on the host's microbiome and secondary infection which also worsen the disease. Twit Text FOAVip Host factors facilitating SARS-CoV-2 virus infection and replication in the lungs ????Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=34223911 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34223911 #FOAvip English Wikipedia <ref>{{Cite pmid|34223911}}</ref> Host factors facilitating SARS-CoV-2 virus infection and replication in the lungs #MMPMID34223911 Boutin S; Hildebrand D; Boulant S; Kreuter M; Ruter J; Pallerla SR; Velavan TP; Nurjadi D Cell Mol Life Sci 2021[Aug]; 78 (16): 5953-5976 PMID34223911show ga SARS-CoV-2 is the virus causing the major pandemic facing the world today. Although, SARS-CoV-2 primarily causes lung infection, a variety of symptoms have proven a systemic impact on the body. SARS-CoV-2 has spread in the community quickly infecting humans from all age, ethnicities and gender. However, fatal outcomes have been linked to specific host factors and co-morbidities such as age, hypertension, immuno-deficiencies, chronic lung diseases or metabolic disorders. A major shift in the microbiome of patients suffering of the coronavirus disease 2019 (COVID-19) have also been observed and is linked to a worst outcome of the disease. As many co-morbidities are already known to be associated with a dysbiosis of the microbiome such as hypertension, diabetes and metabolic disorders. Host factors and microbiome changes are believed to be involved as a network in the acquisition of the infection and the development of the diseases. We will review in detail in this manuscript, the immune response toward SARS-CoV-2 infection as well as the host factors involved in the facilitation and worsening of the infection. We will also address the impact of COVID-19 on the host's microbiome and secondary infection which also worsen the disease. |Animals[MESH] |COVID-19/*immunology/*virology[MESH] |Dysbiosis/immunology/virology[MESH] |Humans[MESH] |Immunity/immunology[MESH] |Lung/*immunology/*virology[MESH] |Microbiota/immunology[MESH] |Pandemics[MESH] |SARS-CoV-2/*immunology[MESH]Host factors facilitating SARS-CoV-2 virus infection and replication i(epmc).pdf DeepDyve Pubget Overpricing