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10.1016/j.dsx.2021.102189

http://scihub22266oqcxt.onion/10.1016/j.dsx.2021.102189
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suck abstract from ncbi

pmid34217144      Diabetes+Metab+Syndr 2021 ; 15 (4): 102189
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  • "Vitamin D supplementation and COVID-19 treatment: A systematic review and meta-analysis" #MMPMID34217144
  • Rawat D; Roy A; Maitra S; Shankar V; Khanna P; Baidya DK
  • Diabetes Metab Syndr 2021[Jul]; 15 (4): 102189 PMID34217144show ga
  • BACKGROUND: Vitamin-D is an immune-modulator which might be linked to disease severity by SARS-CoV-2. METHODS: Meta-analysis of RCTs and quasi-experimental studies, evaluating the role of vitamin-D supplementation in COVID patients was done. RESULTS: Total 5 studies (3 RCTs and 2 Quasi-experimental) including n = 467 patients were included. Vitamin D didn't reduce mortality (RR 0.55, 95%CI 0.22 to 1.39, p = 0.21), ICU admission rates (RR 0.20, 95% CI 0.01-4.26, p = 0.3) and need for invasive ventilation (RR 0.24, 95% CI 0.01-7.89, p = 0.42). CONCLUSION: No significant difference with vitamin-D supplementation on major health related outcomes in COVID-19. Well-designed RCTs are required addressing this topic.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Dietary Supplements[MESH]
  • |COVID-19/epidemiology/virology[MESH]
  • |Humans[MESH]
  • |Nutrition Therapy/*methods[MESH]
  • |Prognosis[MESH]
  • |SARS-CoV-2/*drug effects[MESH]
  • |Vitamin D/*administration & dosage[MESH]


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