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10.1007/s40477-021-00605-8

http://scihub22266oqcxt.onion/10.1007/s40477-021-00605-8
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suck abstract from ncbi


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pmid34213740      J+Ultrasound 2022 ; 25 (3): 457-467
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  • Lung ultrasound findings in hospitalized COVID-19 patients in relation to venous thromboembolic events: the ECHOVID-19 study #MMPMID34213740
  • Skaarup KG; Lassen MCH; Espersen C; Lind JN; Johansen ND; Sengelov M; Alhakak AS; Nielsen AB; Ravnkilde K; Hauser R; Schops LB; Holt E; Bundgaard H; Hassager C; Jabbari R; Carlsen J; Kirk O; Bodtger U; Lindholm MG; Wiese L; Kristiansen OP; Walsted ES; Nielsen OW; Lindegaard B; Tonder N; Jeschke KN; Ulrik CS; Lamberts M; Sivapalan P; Pallisgaard J; Gislason G; Iversen K; Jensen JUS; Schou M; Skaarup SH; Platz E; Biering-Sorensen T
  • J Ultrasound 2022[Sep]; 25 (3): 457-467 PMID34213740show ga
  • PURPOSE: Several studies have reported thromboembolic events to be common in severe COVID-19 cases. We sought to investigate the relationship between lung ultrasound (LUS) findings in hospitalized COVID-19 patients and the development of venous thromboembolic events (VTE). METHODS: A total of 203 adults were included from a COVID-19 ward in this prospective multi-center study (mean age 68.6 years, 56.7% men). All patients underwent 8-zone LUS, and all ultrasound images were analyzed off-line blinded. Several LUS findings were investigated (total number of B-lines, B-line score, and LUS-scores). RESULTS: Median time from admission to LUS examination was 4 days (IQR: 2, 8). The median number of B-lines was 12 (IQR: 8, 18), and 44 (21.7%) had a positive B-line score. During hospitalization, 17 patients developed VTE (4 deep-vein thrombosis, 15 pulmonary embolism), 12 following and 5 prior to LUS. In fully adjusted multivariable Cox models (excluding participants with VTE prior to LUS), all LUS parameters were significantly associated with VTE (total number of B-lines: HR = 1.14, 95% CI (1.03, 1.26) per 1 B-line increase), positive B-line score: HR = 9.79, 95% CI (1.87, 51.35), and LUS-score: HR = 1.51, 95% CI (1.10, 2.07), per 1-point increase). The B-line score and LUS-score remained significantly associated with VTE in sensitivity analyses. CONCLUSION: In hospitalized COVID-19 patients, pathological LUS findings were common, and the total number of B-lines, B-line score, and LUS-score were all associated with VTE. These findings indicate that the LUS examination may be useful in risk stratification and the clinical management of COVID-19. These findings should be considered hypothesis generating. GOV ID: NCT04377035.
  • |*COVID-19/diagnostic imaging[MESH]
  • |*Venous Thromboembolism/diagnostic imaging[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Male[MESH]
  • |Prospective Studies[MESH]


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