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10.1183/13993003.01341-2021

http://scihub22266oqcxt.onion/10.1183/13993003.01341-2021
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suck abstract from ncbi


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pmid34210789      Eur+Respir+J 2022 ; 59 (2): ä
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  • Risk factors for post-COVID-19 condition in previously hospitalised children using the ISARIC Global follow-up protocol: a prospective cohort study #MMPMID34210789
  • Osmanov IM; Spiridonova E; Bobkova P; Gamirova A; Shikhaleva A; Andreeva M; Blyuss O; El-Taravi Y; DunnGalvin A; Comberiati P; Peroni DG; Apfelbacher C; Genuneit J; Mazankova L; Miroshina A; Chistyakova E; Samitova E; Borzakova S; Bondarenko E; Korsunskiy AA; Konova I; Hanson SW; Carson G; Sigfrid L; Scott JT; Greenhawt M; Whittaker EA; Garralda E; Swann OV; Buonsenso D; Nicholls DE; Simpson F; Jones C; Semple MG; Warner JO; Vos T; Olliaro P; Munblit D
  • Eur Respir J 2022[Feb]; 59 (2): ä PMID34210789show ga
  • BACKGROUND: The long-term sequelae of coronavirus disease 2019 (COVID-19) in children remain poorly characterised. This study aimed to assess long-term outcomes in children previously hospitalised with COVID-19 and associated risk factors. METHODS: This is a prospective cohort study of children (5 months) were further categorised by system(s) involved. RESULTS: 518 out of 853 (61%) eligible children were available for the follow-up assessment and included in the study. Median (interquartile range (IQR)) age was 10.4 (3-15.2) years and 270 (52.1%) were girls. Median (IQR) follow-up since hospital discharge was 256 (223-271) days. At the time of the follow-up interview 126 (24.3%) participants reported persistent symptoms, among which fatigue (53, 10.7%), sleep disturbance (36, 6.9%) and sensory problems (29, 5.6%) were the most common. Multiple symptoms were experienced by 44 (8.4%) participants. Risk factors for persistent symptoms were: older age "6-11 years" (OR 2.74, 95% CI 1.37-5.75) and "12-18 years" (OR 2.68, 95% CI 1.41-5.4), and a history of allergic diseases (OR 1.67, 95% CI 1.04-2.67). CONCLUSIONS: A quarter of children experienced persistent symptoms months after hospitalisation with acute COVID-19 infection, with almost one in 10 experiencing multisystem involvement. Older age and allergic diseases were associated with higher risk of persistent symptoms at follow-up.
  • |*COVID-19[MESH]
  • |Adolescent[MESH]
  • |Aged[MESH]
  • |Child[MESH]
  • |Child, Hospitalized[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Prospective Studies[MESH]
  • |Risk Factors[MESH]


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