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10.3390/microorganisms9061259

http://scihub22266oqcxt.onion/10.3390/microorganisms9061259
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34207902!8229673!34207902
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suck abstract from ncbi


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pmid34207902      Microorganisms 2021 ; 9 (6): ä
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  • KI and WU Polyomavirus in Respiratory Samples of SARS-CoV-2 Infected Patients #MMPMID34207902
  • Prezioso C; Moens U; Oliveto G; Brazzini G; Piacentini F; Frasca F; Viscido A; Scordio M; Guerrizio G; Rodio DM; Pierangeli A; d'Ettorre G; Turriziani O; Antonelli G; Scagnolari C; Pietropaolo V
  • Microorganisms 2021[Jun]; 9 (6): ä PMID34207902show ga
  • Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a global pandemic. Our goal was to determine whether co-infections with respiratory polyomaviruses, such as Karolinska Institutet polyomavirus (KIPyV) and Washington University polyomavirus (WUPyV) occur in SARS-CoV-2 infected patients. Oropharyngeal swabs from 150 individuals, 112 symptomatic COVID-19 patients and 38 healthcare workers not infected by SARS-CoV-2, were collected from March 2020 through May 2020 and tested for KIPyV and WUPyV DNA presence. Of the 112 SARS-CoV-2 positive patients, 27 (24.1%) were co-infected with KIPyV, 5 (4.5%) were positive for WUPyV, and 3 (2.7%) were infected simultaneously by KIPyV and WUPyV. Neither KIPyV nor WUPyV DNA was detected in samples of healthcare workers. Significant correlations were found in patients co-infected with SARS-CoV-2 and KIPyV (p < 0.05) and between SARS-CoV-2 cycle threshold values and KIPyV, WUPyV and KIPyV and WUPyV concurrently detected (p < 0.05). These results suggest that KIPyV and WUPyV may behave as opportunistic respiratory pathogens. Additional investigations are needed to understand the epidemiology and the prevalence of respiratory polyomavirus in COVID-19 patients and whether KIPyV and WUPyV could potentially drive viral interference or influence disease outcomes by upregulating SARS-CoV-2 replicative potential.
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