Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3390/ijms22115980 http://scihub22266oqcxt.onion/10.3390/ijms22115980 34205975!8197836!34205975     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2021 ; 22 (11): ä Nephropedia Template TP {{tp|p=34205975|t=2021. Multifaced Roles of HDL in Sepsis and SARS-CoV-2 Infection: Renal Implications |pdf=|usr=}}{{34205975}} gab.com Text Multifaced Roles of HDL in Sepsis and SARS-CoV-2 Infection: Renal Implications JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=34205975 #FOAvip High-density lipoproteins (HDLs) are a class of blood particles, principally involved in mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches have identified crucial mediators in the HDL proteomic and lipidomic profile, which are involved in distinct pleiotropic functions. Besides their role as cholesterol transporter, HDLs display anti-inflammatory, anti-apoptotic, anti-thrombotic, and anti-infection properties. Experimental and clinical studies have unveiled significant changes in both HDL serum amount and composition that lead to dysregulated host immune response and endothelial dysfunction in the course of sepsis. Most SARS-Coronavirus-2-infected patients admitted to the intensive care unit showed common features of sepsis disease, such as the overwhelmed systemic inflammatory response and the alterations in serum lipid profile. Despite relevant advances, episodes of mild to moderate acute kidney injury (AKI), occurring during systemic inflammatory diseases, are associated with long-term complications, and high risk of mortality. The multi-faceted relationship of kidney dysfunction with dyslipidemia and inflammation encourages to deepen the clarification of the mechanisms connecting these elements. This review analyzes the multifaced roles of HDL in inflammatory diseases, the renal involvement in lipid metabolism, and the novel potential HDL-based therapies. Twit Text FOAVip Multifaced Roles of HDL in Sepsis and SARS-CoV-2 Infection: Renal Implications ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=34205975 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34205975 #FOAvip English Wikipedia <ref>{{Cite pmid|34205975}}</ref> Multifaced Roles of HDL in Sepsis and SARS-CoV-2 Infection: Renal Implications #MMPMID34205975 Stasi A; Franzin R; Fiorentino M; Squiccimarro E; Castellano G; Gesualdo L Int J Mol Sci 2021[Jun]; 22 (11): ä PMID34205975show ga High-density lipoproteins (HDLs) are a class of blood particles, principally involved in mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches have identified crucial mediators in the HDL proteomic and lipidomic profile, which are involved in distinct pleiotropic functions. Besides their role as cholesterol transporter, HDLs display anti-inflammatory, anti-apoptotic, anti-thrombotic, and anti-infection properties. Experimental and clinical studies have unveiled significant changes in both HDL serum amount and composition that lead to dysregulated host immune response and endothelial dysfunction in the course of sepsis. Most SARS-Coronavirus-2-infected patients admitted to the intensive care unit showed common features of sepsis disease, such as the overwhelmed systemic inflammatory response and the alterations in serum lipid profile. Despite relevant advances, episodes of mild to moderate acute kidney injury (AKI), occurring during systemic inflammatory diseases, are associated with long-term complications, and high risk of mortality. The multi-faceted relationship of kidney dysfunction with dyslipidemia and inflammation encourages to deepen the clarification of the mechanisms connecting these elements. This review analyzes the multifaced roles of HDL in inflammatory diseases, the renal involvement in lipid metabolism, and the novel potential HDL-based therapies. |Acute Kidney Injury/etiology[MESH] |COVID-19/complications/metabolism/*pathology/virology[MESH] |Cholesterol/metabolism[MESH] |Complement System Proteins/metabolism[MESH] |Humans[MESH] |Lipid Metabolism[MESH] |Lipoproteins, HDL/chemistry/*metabolism[MESH] |SARS-CoV-2/isolation & purification/physiology[MESH] |Sepsis/complications/metabolism/*pathology[MESH]Multifaced Roles of HDL in Sepsis and SARS-CoV-2 Infection: Renal Impl(epmc).pdf DeepDyve Pubget Overpricing