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10.3390/biom11060876 http://scihub22266oqcxt.onion/10.3390/biom11060876 34204735!8231494!34204735     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomolecules 2021 ; 11 (6): ä Nephropedia Template TP {{tp|p=34204735|t=2021. Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19-The Role of RAGE-RAS Crosstalk |pdf=|usr=}}{{34204735}} gab.com Text Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19-The Role of RAGE-RAS Crosstalk JO: Biomolecules http://www.kidney.de/pget.php?&tw=1&pmid=34204735 #FOAvip The receptor for advanced glycation-end products (RAGE) is a multiligand receptor with a role in inflammatory and pulmonary pathologies. Hyperactivation of RAGE by its ligands has been reported to sustain inflammation and oxidative stress in common comorbidities of severe COVID-19. RAGE is essential to the deleterious effects of the renin-angiotensin system (RAS), which participates in infection and multiorgan injury in COVID-19 patients. Thus, RAGE might be a major player in severe COVID-19, and appears to be a useful therapeutic molecular target in infections by SARS-CoV-2. The role of RAGE gene polymorphisms in predisposing patients to severe COVID-19 is discussed. . Twit Text FOAVip Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19-The Role of RAGE-RAS Crosstalk ????Biomolecules http://www.kidney.de/pget.php?&tw=1&pmid=34204735 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34204735 #FOAvip English Wikipedia <ref>{{Cite pmid|34204735}}</ref> Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19-The Role of RAGE-RAS Crosstalk #MMPMID34204735 Chiappalupi S; Salvadori L; Donato R; Riuzzi F; Sorci G Biomolecules 2021[Jun]; 11 (6): ä PMID34204735show ga The receptor for advanced glycation-end products (RAGE) is a multiligand receptor with a role in inflammatory and pulmonary pathologies. Hyperactivation of RAGE by its ligands has been reported to sustain inflammation and oxidative stress in common comorbidities of severe COVID-19. RAGE is essential to the deleterious effects of the renin-angiotensin system (RAS), which participates in infection and multiorgan injury in COVID-19 patients. Thus, RAGE might be a major player in severe COVID-19, and appears to be a useful therapeutic molecular target in infections by SARS-CoV-2. The role of RAGE gene polymorphisms in predisposing patients to severe COVID-19 is discussed. . |*Oxidative Stress[MESH] |*Renin-Angiotensin System[MESH] |Animals[MESH] |COVID-19/genetics/*metabolism/pathology[MESH] |Humans[MESH] |Inflammation/genetics/*metabolism/pathology[MESH] |Polymorphism, Genetic[MESH] |Receptor for Advanced Glycation End Products/genetics/*metabolism[MESH] |Risk Factors[MESH] |SARS-CoV-2/physiology[MESH]Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID(epmc).pdf DeepDyve Pubget Overpricing