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10.3390/nu13072173 http://scihub22266oqcxt.onion/10.3390/nu13072173 34202697!8308355!34202697     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nutrients 2021 ; 13 (7): ä Nephropedia Template TP {{tp|p=34202697|t=2021. Vitamin A Plasma Levels in COVID-19 Patients: A Prospective Multicenter Study and Hypothesis |pdf=|usr=}}{{34202697}} gab.com Text Vitamin A Plasma Levels in COVID-19 Patients: A Prospective Multicenter Study and Hypothesis JO: Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=34202697 #FOAvip COVID-19 is a pandemic disease that causes severe pulmonary damage and hyperinflammation. Vitamin A is a crucial factor in the development of immune functions and is known to be reduced in cases of acute inflammation. This prospective, multicenter observational cross-sectional study analyzed vitamin A plasma levels in SARS-CoV-2 infected individuals, and 40 hospitalized patients were included. Of these, 22 developed critical disease (Acute Respiratory Distress Syndrome [ARDS]/Extracorporeal membrane oxygenation [ECMO]), 9 developed severe disease (oxygen supplementation), and 9 developed moderate disease (no oxygen supplementation). A total of 47 age-matched convalescent persons that had been earlier infected with SARS-CoV-2 were included as the control group. Vitamin A plasma levels were determined by high-performance liquid chromatography. Reduced vitamin A plasma levels correlated significantly with increased levels of inflammatory markers (CRP, ferritin) and with markers of acute SARS-CoV-2 infection (reduced lymphocyte count, LDH). Vitamin A levels were significantly lower in hospitalized patients than in convalescent persons (p < 0.01). Of the hospitalized patients, those who were critically ill showed significantly lower vitamin A levels than those who were moderately ill (p < 0.05). Vitamin A plasma levels below 0.2 mg/L were significantly associated with the development of ARDS (OR = 5.54 [1.01-30.26]; p = 0.048) and mortality (OR 5.21 [1.06-25.5], p = 0.042). Taken together, we conclude that vitamin A plasma levels in COVID-19 patients are reduced during acute inflammation and that severely reduced plasma levels of vitamin A are significantly associated with ARDS and mortality. Twit Text FOAVip Vitamin A Plasma Levels in COVID-19 Patients: A Prospective Multicenter Study and Hypothesis ????Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=34202697 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34202697 #FOAvip English Wikipedia <ref>{{Cite pmid|34202697}}</ref> Vitamin A Plasma Levels in COVID-19 Patients: A Prospective Multicenter Study and Hypothesis #MMPMID34202697 Tepasse PR; Vollenberg R; Fobker M; Kabar I; Schmidt H; Meier JA; Nowacki T; Husing-Kabar A Nutrients 2021[Jun]; 13 (7): ä PMID34202697show ga COVID-19 is a pandemic disease that causes severe pulmonary damage and hyperinflammation. Vitamin A is a crucial factor in the development of immune functions and is known to be reduced in cases of acute inflammation. This prospective, multicenter observational cross-sectional study analyzed vitamin A plasma levels in SARS-CoV-2 infected individuals, and 40 hospitalized patients were included. Of these, 22 developed critical disease (Acute Respiratory Distress Syndrome [ARDS]/Extracorporeal membrane oxygenation [ECMO]), 9 developed severe disease (oxygen supplementation), and 9 developed moderate disease (no oxygen supplementation). A total of 47 age-matched convalescent persons that had been earlier infected with SARS-CoV-2 were included as the control group. Vitamin A plasma levels were determined by high-performance liquid chromatography. Reduced vitamin A plasma levels correlated significantly with increased levels of inflammatory markers (CRP, ferritin) and with markers of acute SARS-CoV-2 infection (reduced lymphocyte count, LDH). Vitamin A levels were significantly lower in hospitalized patients than in convalescent persons (p < 0.01). Of the hospitalized patients, those who were critically ill showed significantly lower vitamin A levels than those who were moderately ill (p < 0.05). Vitamin A plasma levels below 0.2 mg/L were significantly associated with the development of ARDS (OR = 5.54 [1.01-30.26]; p = 0.048) and mortality (OR 5.21 [1.06-25.5], p = 0.042). Taken together, we conclude that vitamin A plasma levels in COVID-19 patients are reduced during acute inflammation and that severely reduced plasma levels of vitamin A are significantly associated with ARDS and mortality. |Adult[MESH] |Aged[MESH] |Biomarkers/blood[MESH] |C-Reactive Protein/analysis[MESH] |COVID-19/*blood/mortality[MESH] |Chromatography, Liquid/methods[MESH] |Critical Illness[MESH] |Cross-Sectional Studies[MESH] |Extracorporeal Membrane Oxygenation/statistics & numerical data[MESH] |Female[MESH] |Ferritins/blood[MESH] |Hospitalization[MESH] |Humans[MESH] |Inflammation/epidemiology[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Middle Aged[MESH] |Prospective Studies[MESH] |Respiratory Distress Syndrome/epidemiology[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH]Vitamin A Plasma Levels in COVID-19 Patients: A Prospective Multicente(epmc).pdf DeepDyve Pubget Overpricing