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10.3390/v13061115

http://scihub22266oqcxt.onion/10.3390/v13061115
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34200602!8227405!34200602
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suck abstract from ncbi


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pmid34200602      Viruses 2021 ; 13 (6): ä
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  • The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral Structure, Biological Functions, and a Potential Target for Drug or Vaccine Mitigation #MMPMID34200602
  • Bai Z; Cao Y; Liu W; Li J
  • Viruses 2021[Jun]; 13 (6): ä PMID34200602show ga
  • The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the world is still expanding. Thus, there is an urgent need to better understand this novel virus and find a way to control its spread. Like other coronaviruses, the nucleocapsid (N) protein is one of the most crucial structural components of SARS-CoV-2. This protein shares 90% homology with the severe acute respiratory syndrome coronavirus N protein, implying functional significance. Based on the evolutionary conservation of the N protein in coronavirus, we reviewed the currently available knowledge regarding the SARS-CoV-2 N protein in terms of structure, biological functions, and clinical application as a drug target or vaccine candidate.
  • |Animals[MESH]
  • |Antiviral Agents/pharmacology[MESH]
  • |COVID-19 Vaccines/*immunology[MESH]
  • |COVID-19/prevention & control[MESH]
  • |Coronavirus Nucleocapsid Proteins/immunology/*metabolism[MESH]
  • |Humans[MESH]
  • |Mice[MESH]
  • |Pharmaceutical Preparations[MESH]
  • |SARS-CoV-2/*chemistry/drug effects/immunology/*metabolism[MESH]


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