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10.3390/children8060477

http://scihub22266oqcxt.onion/10.3390/children8060477
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34200043!8229205!34200043
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suck abstract from ncbi


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pmid34200043      Children+(Basel) 2021 ; 8 (6): ä
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  • Respiratory Failure in an Extremely Premature Neonate with COVID-19 #MMPMID34200043
  • Kumar VHS; Prasath A; Blanco C; Kenney PO; Ostwald CM; Meyer TS; Clementi CF; Maciejewski R; Wilby MT; Reynolds AM; Hpa NJ; Yu KOA
  • Children (Basel) 2021[Jun]; 8 (6): ä PMID34200043show ga
  • Coronavirus disease 2019 (COVID-19), a condition associated with SARS-CoV-2, typically results in mild infection in infants and children. However, children with risk factors such as chronic lung disease and immunosuppression have higher risk of severe illness from COVID-19. We report a case of a 27-week-gestation extremely premature infant born to a mother with COVID-19 infection. The infant, initially treated for surfactant deficiency, developed worsening hypoxic respiratory failure on the fifth day of life requiring escalating ventilatory support, an elevated level of C-reactive protein, thrombocytopenia, and an elevated level of d-dimer. The infant was positive for SARS-CoV-2 by RT-PCR from Day 1 to Day 42 of his life. The infant responded to a seven-day course of dexamethasone with a gradually decreasing oxygen requirement and could be extubated to non-invasive ventilation by the end of the fifth week after birth. The infant is currently on home oxygen by nasal cannula. Prolonged shedding of the virus may be a unique feature of the disease in premature infants. Extreme prematurity, immature lungs, and an immunocompromised status may predispose these infants to severe respiratory failure and a prolonged clinical course. Instituting appropriate COVID-19 protocols to prevent the spread of the disease in the neonatal intensive care unit (NICU) is of utmost importance. Infection with SARS-CoV-2 may have implications in the management of extremely premature infants in the NICU.
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