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10.4103/jgid.jgid_316_20

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34194176!8213088!34194176
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suck abstract from ncbi


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pmid34194176      J+Glob+Infect+Dis 2021 ; 13 (2): 91-93
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  • Evaluation of COVID-19 Antigen Fluorescence Immunoassay Test for Rapid Detection of SARS-CoV-2 #MMPMID34194176
  • Kiro VV; Gupta A; Singh P; Sharad N; Khurana S; Prakash S; Dar L; Malhotra R; Wig N; Kumar A; Trikha A; Mathur P
  • J Glob Infect Dis 2021[Apr]; 13 (2): 91-93 PMID34194176show ga
  • INTRODUCTION: Tests detecting SARS-CoV-2-specific antigen have recently been developed, and many of them are now commercially available. However, the real-world performance of these assays is uncertain; therefore, their validation is important. In this study, we have evaluated the performance of STANDARD F COVID-19 antigen fluorescence immunoassay (FIA) kit. METHODS: Nasopharyngeal samples collected from patients were subjected to the test as per manufacturer's instructions. The performance of the kit was compared with the gold standard real-time polymerase chain reaction. RESULTS: A total of 354 patients were tested with STANDARD F COVID-19 antigen FIA test kit. The overall sensitivity, specificity, positive predictive value, and negative predictive value of this test were found to be 38%, 99%, 96.2%, and 72%, respectively, with a diagnostic accuracy of 75.7%. CONCLUSION: STANDARD F COVID-19 antigen FIA showed high specificity and positive predictive value but low sensitivity and negative predictive value.
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