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10.1186/s13054-021-03639-w http://scihub22266oqcxt.onion/10.1186/s13054-021-03639-w 34193220!8243043!34193220     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Crit+Care 2021 ; 25 (1): 224 Nephropedia Template TP {{tp|p=34193220|t=2021. Timing and causes of death in severe COVID-19 patients |pdf=|usr=}}{{34193220}} gab.com Text Timing and causes of death in severe COVID-19 patients JO: Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=34193220 #FOAvip BACKGROUND: Previous studies reporting the causes of death in patients with severe COVID-19 have provided conflicting results. The objective of this study was to describe the causes and timing of death in patients with severe COVID-19 admitted to the intensive care unit (ICU). METHODS: We performed a retrospective study in eight ICUs across seven French hospitals. All consecutive adult patients (aged >/= 18 years) admitted to the ICU with PCR-confirmed SARS-CoV-2 infection and acute respiratory failure were included in the analysis. The causes and timing of ICU deaths were reported based on medical records. RESULTS: From March 1, 2020, to April 28, 287 patients were admitted to the ICU for SARS-CoV-2 related acute respiratory failure. Among them, 93 patients died in the ICU (32%). COVID-19-related multiple organ dysfunction syndrome (MODS) was the leading cause of death (37%). Secondary infection-related MODS accounted for 26% of ICU deaths, with a majority of ventilator-associated pneumonia. Refractory hypoxemia/pulmonary fibrosis was responsible for death in 19% of the cases. Fatal ischemic events (venous or arterial) occurred in 13% of the cases. The median time from ICU admission to death was 15 days (25th-75th IQR, 7-27 days). COVID-19-related MODS had a median time from ICU admission to death of 14 days (25th-75th IQR: 7-19 days), while only one death had occurred during the first 3 days since ICU admission. CONCLUSIONS: In our multicenter observational study, COVID-19-related MODS and secondary infections were the two leading causes of death, among severe COVID-19 patients admitted to the ICU. Twit Text FOAVip Timing and causes of death in severe COVID-19 patients ????Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=34193220 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34193220 #FOAvip English Wikipedia <ref>{{Cite pmid|34193220}}</ref> Timing and causes of death in severe COVID-19 patients #MMPMID34193220 de Roquetaillade C; Bredin S; Lascarrou JB; Soumagne T; Cojocaru M; Chousterman BG; Leclerc M; Gouhier A; Piton G; Pene F; Stoclin A; Llitjos JF Crit Care 2021[Jun]; 25 (1): 224 PMID34193220show ga BACKGROUND: Previous studies reporting the causes of death in patients with severe COVID-19 have provided conflicting results. The objective of this study was to describe the causes and timing of death in patients with severe COVID-19 admitted to the intensive care unit (ICU). METHODS: We performed a retrospective study in eight ICUs across seven French hospitals. All consecutive adult patients (aged >/= 18 years) admitted to the ICU with PCR-confirmed SARS-CoV-2 infection and acute respiratory failure were included in the analysis. The causes and timing of ICU deaths were reported based on medical records. RESULTS: From March 1, 2020, to April 28, 287 patients were admitted to the ICU for SARS-CoV-2 related acute respiratory failure. Among them, 93 patients died in the ICU (32%). COVID-19-related multiple organ dysfunction syndrome (MODS) was the leading cause of death (37%). Secondary infection-related MODS accounted for 26% of ICU deaths, with a majority of ventilator-associated pneumonia. Refractory hypoxemia/pulmonary fibrosis was responsible for death in 19% of the cases. Fatal ischemic events (venous or arterial) occurred in 13% of the cases. The median time from ICU admission to death was 15 days (25th-75th IQR, 7-27 days). COVID-19-related MODS had a median time from ICU admission to death of 14 days (25th-75th IQR: 7-19 days), while only one death had occurred during the first 3 days since ICU admission. CONCLUSIONS: In our multicenter observational study, COVID-19-related MODS and secondary infections were the two leading causes of death, among severe COVID-19 patients admitted to the ICU. |Adult[MESH] |COVID-19/*mortality[MESH] |Cause of Death[MESH] |Female[MESH] |Hospital Mortality[MESH] |Humans[MESH] |Hypoxia/mortality/virology[MESH] |Intensive Care Units[MESH] |Ischemia/mortality/virology[MESH] |Male[MESH] |Multiple Organ Failure/*mortality/virology[MESH] |Pneumonia, Ventilator-Associated/mortality/virology[MESH] |Pneumonia, Viral/*mortality/virology[MESH] |Pulmonary Fibrosis/mortality/virology[MESH] |Retrospective Studies[MESH]Timing and causes of death in severe COVID-19 patients (epmc).pdf DeepDyve Pubget Overpricing