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10.1097/MAT.0000000000001530 http://scihub22266oqcxt.onion/10.1097/MAT.0000000000001530 34191753!8478105!34191753     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ASAIO+J 2021 ; 67 (10): 1087-1096 Nephropedia Template TP {{tp|p=34191753|t=2021. Renal Considerations in COVID-19: Biology, Pathology, and Pathophysiology |pdf=|usr=}}{{34191753}} gab.com Text Renal Considerations in COVID-19: Biology, Pathology, and Pathophysiology JO: ASAIO J http://www.kidney.de/pget.php?&tw=1&pmid=34191753 #FOAvip Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has emerged into a worldwide pandemic of epic proportion. Beyond pulmonary involvement in coronavirus disease 2019 (COVID-19), a significant subset of patients experiences acute kidney injury. Patients who die from severe disease most notably show diffuse acute tubular injury on postmortem examination with a possible contribution of focal macro- and microvascular thrombi. Renal biopsies in patients with proteinuria and hematuria have demonstrated a glomerular dominant pattern of injury, most notably a collapsing glomerulopathy reminiscent of findings seen in human immunodeficiency virus (HIV) in individuals with apolipoprotein L-1 (APOL1) risk allele variants. Although various mechanisms have been proposed for the pathogenesis of acute kidney injury in SARS-CoV-2 infection, direct renal cell infection has not been definitively demonstrated and our understanding of the spectrum of renal involvement remains incomplete. Herein we discuss the biology, pathology, and pathogenesis of SARS-CoV-2 infection and associated renal involvement. We discuss the molecular biology, risk factors, and pathophysiology of renal injury associated with SARS-CoV-2 infection. We highlight the characteristics of specific renal pathologies based on native kidney biopsy and autopsy. Additionally, a brief discussion on ancillary studies and challenges in the diagnosis of SARS-CoV-2 is presented. Twit Text FOAVip Renal Considerations in COVID-19: Biology, Pathology, and Pathophysiology ????ASAIO J http://www.kidney.de/pget.php?&tw=1&pmid=34191753 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34191753 #FOAvip English Wikipedia <ref>{{Cite pmid|34191753}}</ref> Renal Considerations in COVID-19: Biology, Pathology, and Pathophysiology #MMPMID34191753 Kapp ME; Fogo AB; Roufouse C; Najafian B; Radhakrishnan J; Mohan S; Miller SE; D'Agati VD; Silberzweig J; Barbar T; Gopalan T; Srivatana V; Mokrzycki MH; Benstein JA; Ng YH; Lentine KL; Aggarwal V; Perl J; Salenger P; Koyner JL; Josephson MA; Heung M; Velez JC; Ikizler A; Vijayan A; William P; Thajudeen B; Slepian MJ ASAIO J 2021[Oct]; 67 (10): 1087-1096 PMID34191753show ga Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has emerged into a worldwide pandemic of epic proportion. Beyond pulmonary involvement in coronavirus disease 2019 (COVID-19), a significant subset of patients experiences acute kidney injury. Patients who die from severe disease most notably show diffuse acute tubular injury on postmortem examination with a possible contribution of focal macro- and microvascular thrombi. Renal biopsies in patients with proteinuria and hematuria have demonstrated a glomerular dominant pattern of injury, most notably a collapsing glomerulopathy reminiscent of findings seen in human immunodeficiency virus (HIV) in individuals with apolipoprotein L-1 (APOL1) risk allele variants. Although various mechanisms have been proposed for the pathogenesis of acute kidney injury in SARS-CoV-2 infection, direct renal cell infection has not been definitively demonstrated and our understanding of the spectrum of renal involvement remains incomplete. Herein we discuss the biology, pathology, and pathogenesis of SARS-CoV-2 infection and associated renal involvement. We discuss the molecular biology, risk factors, and pathophysiology of renal injury associated with SARS-CoV-2 infection. We highlight the characteristics of specific renal pathologies based on native kidney biopsy and autopsy. Additionally, a brief discussion on ancillary studies and challenges in the diagnosis of SARS-CoV-2 is presented. |*Acute Kidney Injury/pathology/physiopathology[MESH] |COVID-19/*complications/pathology[MESH] |Humans[MESH] |Kidney Tubular Necrosis, Acute/pathology[MESH] |Kidney/*pathology[MESH]Renal Considerations in COVID-19: Biology, Pathology, and Pathophysiol(epmc).pdf DeepDyve Pubget Overpricing