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10.1093/infdis/jiab337 http://scihub22266oqcxt.onion/10.1093/infdis/jiab337 34191025!8448437!34191025     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Infect+Dis 2021 ; 224 (6): 976-982 Nephropedia Template TP {{tp|p=34191025|t=2021. Longitudinal Assessment of Diagnostic Test Performance Over the Course of Acute SARS-CoV-2 Infection |pdf=|usr=}}{{34191025}} gab.com Text Longitudinal Assessment of Diagnostic Test Performance Over the Course of Acute SARS-CoV-2 Infection JO: J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34191025 #FOAvip BACKGROUND: Serial screening is critical for restricting spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by facilitating timely identification of infected individuals to interrupt transmission. Variation in sensitivity of different diagnostic tests at different stages of infection has not been well documented. METHODS: In a longitudinal study of 43 adults newly infected with SARS-CoV-2, all provided daily saliva and nasal swabs for quantitative reverse transcription polymerase chain reaction (RT-qPCR), Quidel SARS Sofia antigen fluorescent immunoassay (FIA), and live virus culture. RESULTS: Both RT-qPCR and Quidel SARS Sofia antigen FIA peaked in sensitivity during the period in which live virus was detected in nasal swabs, but sensitivity of RT-qPCR tests rose more rapidly prior to this period. We also found that serial testing multiple times per week increases the sensitivity of antigen tests. CONCLUSIONS: RT-qPCR tests are more effective than antigen tests at identifying infected individuals prior to or early during the infectious period and thus for minimizing forward transmission (given timely results reporting). All tests showed >98% sensitivity for identifying infected individuals if used at least every 3 days. Daily screening using antigen tests can achieve approximately 90% sensitivity for identifying infected individuals while they are viral culture positive. Twit Text FOAVip Longitudinal Assessment of Diagnostic Test Performance Over the Course of Acute SARS-CoV-2 Infection ????J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34191025 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34191025 #FOAvip English Wikipedia <ref>{{Cite pmid|34191025}}</ref> Longitudinal Assessment of Diagnostic Test Performance Over the Course of Acute SARS-CoV-2 Infection #MMPMID34191025 Smith RL; Gibson LL; Martinez PP; Ke R; Mirza A; Conte M; Gallagher N; Conte A; Wang L; Fredrickson R; Edmonson DC; Baughman ME; Chiu KK; Choi H; Jensen TW; Scardina KR; Bradley S; Gloss SL; Reinhart C; Yedetore J; Owens AN; Broach J; Barton B; Lazar P; Henness D; Young T; Dunnett A; Robinson ML; Mostafa HH; Pekosz A; Manabe YC; Heetderks WJ; McManus DD; Brooke CB J Infect Dis 2021[Sep]; 224 (6): 976-982 PMID34191025show ga BACKGROUND: Serial screening is critical for restricting spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by facilitating timely identification of infected individuals to interrupt transmission. Variation in sensitivity of different diagnostic tests at different stages of infection has not been well documented. METHODS: In a longitudinal study of 43 adults newly infected with SARS-CoV-2, all provided daily saliva and nasal swabs for quantitative reverse transcription polymerase chain reaction (RT-qPCR), Quidel SARS Sofia antigen fluorescent immunoassay (FIA), and live virus culture. RESULTS: Both RT-qPCR and Quidel SARS Sofia antigen FIA peaked in sensitivity during the period in which live virus was detected in nasal swabs, but sensitivity of RT-qPCR tests rose more rapidly prior to this period. We also found that serial testing multiple times per week increases the sensitivity of antigen tests. CONCLUSIONS: RT-qPCR tests are more effective than antigen tests at identifying infected individuals prior to or early during the infectious period and thus for minimizing forward transmission (given timely results reporting). All tests showed >98% sensitivity for identifying infected individuals if used at least every 3 days. Daily screening using antigen tests can achieve approximately 90% sensitivity for identifying infected individuals while they are viral culture positive. |*COVID-19 Testing[MESH] |*Diagnostic Tests, Routine[MESH] |Adult[MESH] |Aged[MESH] |Animals[MESH] |Antigens, Viral/analysis[MESH] |COVID-19/*diagnosis[MESH] |Chlorocebus aethiops[MESH] |Female[MESH] |Humans[MESH] |Longitudinal Studies[MESH] |Male[MESH] |Mass Screening[MESH] |Middle Aged[MESH] |Real-Time Polymerase Chain Reaction[MESH] |SARS-CoV-2/*isolation & purification[MESH] |Saliva[MESH] |Sensitivity and Specificity[MESH] |Vero Cells[MESH]Longitudinal Assessment of Diagnostic Test Performance Over the Course(epmc).pdf DeepDyve Pubget Overpricing