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10.1016/j.vaccine.2021.06.045

http://scihub22266oqcxt.onion/10.1016/j.vaccine.2021.06.045
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34187707!8216866!34187707
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suck abstract from ncbi


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pmid34187707      Vaccine 2021 ; 39 (32): 4414-4418
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  • Recent MMR vaccination in health care workers and Covid-19: A test negative case-control study #MMPMID34187707
  • Lundberg L; Bygdell M; Stukat von Feilitzen G; Woxenius S; Ohlsson C; Kindblom JM; Leach S
  • Vaccine 2021[Jul]; 39 (32): 4414-4418 PMID34187707show ga
  • BACKGROUND: It has been hypothesised that the measles-mumps-rubella (MMR) vaccine may afford cross-protection against SARS-CoV-2 which may contribute to the wide variability in disease severity of Covid-19. METHODS: We employed a test negative case-control study, utilising a recent measles outbreak during which many healthcare workers received the MMR vaccine, to investigate the potential protective effect of MMR against SARS-CoV-2 in 5905 subjects (n = 805 males, n = 5100 females). RESULTS: The odds ratio for testing positive for SARS-CoV-2, in recently MMR-vaccinated compared to not recently MMR-vaccinated individuals was 0.91 (95% CI 0.76, 1.09). An interaction analysis showed a significant interaction for sex. After sex-stratification, the odds ratio for testing positive for males was 0.43 (95% CI 0.24, 0.79, P = 0.006), and 1.01 (95% CI 0.83, 1.22, P = 0.92) for females. CONCLUSION: Our results indicate that there may be a protective effect of the MMR vaccine against SARS-CoV-2 in males but not females.
  • |*COVID-19[MESH]
  • |*Measles/prevention & control[MESH]
  • |*Mumps[MESH]
  • |*Rubella[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Case-Control Studies[MESH]
  • |Female[MESH]
  • |Health Personnel[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Measles-Mumps-Rubella Vaccine[MESH]
  • |SARS-CoV-2[MESH]


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