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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Lab+Med 2022 ; 53 (1): e1-e3 Nephropedia Template TP
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A Persistent Positive Antibody Test in a Patient with No History of COVID-19 Infection #MMPMID34184052
McMurry J; Fink E
Lab Med 2022[Jan]; 53 (1): e1-e3 PMID34184052show ga
Antibody testing for SARS-CoV-2 has been established as a tool with broad utility in the surveillance and control of the COVID-19 pandemic. However, because of limited knowledge about the duration of humoral immunity to COVID-19 and the existence of unique individual immune responses, the potential role of antibody testing in the diagnosis of current and past infections of COVID-19 remains ambiguous. Herein, we describe a unique case of an asymptomatic patient showing a persistent positive total antibody test for SARS-CoV-2 while testing negative for SARS-CoV-2 RNA and IgG-specific antibodies. This case study shows how a combination of tests can be employed to identify a false positive and draw conclusions about a patient's COVID-19 status. It also highlights the complexity of using antibody testing for the diagnosis of COVID-19.