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10.1007/s13312-021-2330-3

http://scihub22266oqcxt.onion/10.1007/s13312-021-2330-3
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34183466!8549596!34183466
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suck abstract from ncbi


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pmid34183466      Indian+Pediatr 2021 ; 58 (10): 955-958
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  • Clinical Spectrum of Children With Multisystem Inflammatory Syndrome Associated With SARS-CoV-2 Infection #MMPMID34183466
  • Chandran J; James EJ; Verghese VP; Kumar TS; Sundaravalli EKR; Vyasam S
  • Indian Pediatr 2021[Oct]; 58 (10): 955-958 PMID34183466show ga
  • OBJECTIVES: To compare the clinical profile, treatment, and outcomes of PCR-positive and PCR-negative antibody-positive critically ill children with multisystem inflammatory syndrome (MIS-C). METHODS: This retrospective observational study was done at a tertiary care coronavirus disease 19 (COVID-19) pediatric intensive care unit in India. The baseline characteristics, clinical profile, treatment, and outcomes in seventeen critically ill children diagnosed with MIS-C were analyzed from 1 July to 31 October, 2020. RESULTS: Sixteen out of 17 children presented with hypotensive shock and respiratory distress. Mean (SD) age of PCR-negative antibody-positive and PCR-positive children was 11 (4.4) and 5 (3.7) years, respectively (P=0.007). The former group had significantly higher mean (SD) D-dimer levels [16,651 (14859) ng/mL vs 3082 (2591) ng/mL; P=0.02]. All received intensive care management and steroid therapy; 7 children received intravenous immunoglobulin. 14 children survived and 3 died. CONCLUSIONS: The outcome of children with MIS-C was good if recognized early and received intensive care.
  • |*COVID-19/complications[MESH]
  • |*SARS-CoV-2[MESH]
  • |Child[MESH]
  • |Humans[MESH]
  • |Immunoglobulins, Intravenous[MESH]
  • |Intensive Care Units, Pediatric[MESH]


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