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Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Epidemiol+Infect 2021 ; 149 (ä): 1-23 Nephropedia Template TP
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What is the status of nucleic acid contamination in 2019-nCOV vaccination sites? Can it be avoided? #MMPMID34183081
Li Z; Zhang B; Wu X; Yang M; Zhang Q; Xiang G; Chen Y; Zeng L; Tayier D; Zhang W; Song N
Epidemiol Infect 2021[Jun]; 149 (ä): 1-23 PMID34183081show ga
This study aimed to investigate the environmental contamination of nucleic acid at 2019 novel coronavirus (2019-nCOV) vaccination site and to evaluate the effect of improvement to the vaccination process. Nucleic acid samples were collected from the surface of the objects in 2019-nCOV vaccination point A (used between 15 November 2020 and 25 December 2020) and point B (used after 27 December 2020) in a comprehensive tertiary hospital. Samples were collected from point A before improvement to the vaccination process, and from point B (B(1) and B(2)) after improvement to the vaccination process. The real-time fluorescence polymerase chain reaction method was used for detection. The positive rate of vaccination room was 47.06% (24/51) at point A. No positive result was found in point B(1) both at working hours (0/27) and after terminal disinfection (0/27). In point B(2), the positive results were found in vaccine's outer packaging and staff gloves at working hours, with a positive rate of 7.41% (2/27). The positive rate was 0 (0/27) after terminal disinfection in point B(2). The nucleic acid contamination in the vaccination room of 2019-nCOV vaccine nucleic acid sampling point is serious, which can be avoided through the improvement and intervention (such as personal protection, vaccination operation and disinfection methods).