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10.1186/s12871-021-01396-5

http://scihub22266oqcxt.onion/10.1186/s12871-021-01396-5
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suck abstract from ncbi


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pmid34182946      BMC+Anesthesiol 2021 ; 21 (1): 178
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  • Lung ultrasound predicts clinical course but not outcome in COVID-19 ICU patients: a retrospective single-center analysis #MMPMID34182946
  • Stecher SS; Anton S; Fraccaroli A; Gotschke J; Stemmler HJ; Barnikel M
  • BMC Anesthesiol 2021[Jun]; 21 (1): 178 PMID34182946show ga
  • BACKGROUND: Point-of-care lung ultrasound (LU) is an established tool in the first assessment of patients with coronavirus disease (COVID-19). Purpose of this study was to evaluate the value of lung ultrasound in COVID-19 intensive care unit (ICU) patients in predicting clinical course and outcome. METHODS: We analyzed lung ultrasound score (LUS) of all COVID-19 patients admitted from March 2020 to December 2020 to the Internal Intensive Care Unit, Ludwig-Maximilians-University (LMU) of Munich. LU was performed according to a standardized protocol at ICU admission and in case of clinical deterioration with the need for intubation. A normal lung scores 0 points, the worst LUS has 24 points. Patients were stratified in a low (0-12 points) and a high (13-24 points) lung ultrasound score group. RESULTS: The study included 42 patients, 69% of them male. The most common comorbidities were hypertension (81%) and obesity (57%). The values of pH (7.42 +/- 0.09 vs 7.35 +/- 0.1; p = 0.047) and p(a)O(2) (107 [80-130] vs 80 [66-93] mmHg; p = 0.034) were significantly reduced in patients of the high LUS group. Furthermore, the duration of ventilation (12.5 [8.3-25] vs 36.5 [9.8-70] days; p = 0.029) was significantly prolonged in this group. Patchy subpleural thickening (n = 38; 90.5%) and subpleural consolidations (n = 23; 54.8%) were present in most patients. Pleural effusion was rare (n = 4; 9.5%). The median total LUS was 11.9 +/- 3.9 points. In case of clinical deterioration with the need for intubation, LUS worsened significantly compared to baseline LU. Twelve patients died during the ICU stay (29%). There was no difference in survival in both LUS groups (75% vs 66.7%, p = 0.559). CONCLUSIONS: LU can be a useful monitoring tool to predict clinical course but not outcome of COVID-19 ICU patients and can early recognize possible deteriorations.
  • |*SARS-CoV-2[MESH]
  • |Aged[MESH]
  • |COVID-19/*diagnosis/*epidemiology/pathology[MESH]
  • |Critical Care/*methods[MESH]
  • |Female[MESH]
  • |Germany/epidemiology[MESH]
  • |Humans[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Point-of-Care Testing[MESH]
  • |Predictive Value of Tests[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]


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