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10.3389/fimmu.2021.694300

http://scihub22266oqcxt.onion/10.3389/fimmu.2021.694300
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34177959!8226072!34177959
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suck abstract from ncbi


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pmid34177959      Front+Immunol 2021 ; 12 (ä): 694300
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  • Targeting Future Pandemics, a Case for De Novo Purine Synthesis and Basic Research #MMPMID34177959
  • Mazzarino RC
  • Front Immunol 2021[]; 12 (ä): 694300 PMID34177959show ga
  • We are currently experiencing a deadly novel viral pandemic with no efficacious, readily available anti-viral therapies to SARS-CoV-2. Viruses will hijack host cellular machinery, including metabolic processes. Here, I provide theory and evidence for targeting the host de novo purine synthetic pathway for broad spectrum anti-viral drug development as well as the pursuit of basic science to mitigate the risks of future novel viral outbreaks.
  • |*COVID-19 Drug Treatment[MESH]
  • |Animals[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Drug Development[MESH]
  • |Humans[MESH]
  • |Immunity[MESH]
  • |Pandemics[MESH]
  • |Purines/chemical synthesis/*therapeutic use[MESH]
  • |SARS-CoV-2/*physiology[MESH]


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