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10.1016/j.rmed.2021.106469 http://scihub22266oqcxt.onion/10.1016/j.rmed.2021.106469 34175806!8141349!34175806     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34175806&cmd=llinks): Failed to open stream: HTTP request failed! 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Endothelial function provides early prognostic information in patients with COVID-19: A cohort study |pdf=|usr=}}{{34175806}} gab.com Text Endothelial function provides early prognostic information in patients with COVID-19: A cohort study JO: Respir Med http://www.kidney.de/pget.php?&tw=1&pmid=34175806 #FOAvip BACKGROUND: The prothrombotic phenotype and diffuse intravascular coagulation observed in COVID-19 reflect endothelial dysfunction, which is linked to blood flow delivery deficiencies and cardiovascular risk. Assessments of detect vascular deficiencies among newly diagnosed and hospitalized patients due to COVID-19 have yet to be determined. OBJECTIVE: To assess endothelial function characteristics in relation to length of hospitalization and mortality in patients diagnosed with COVID-19 and compare to patients without COVID-19. METHODS: A prospective observational study involving 180 patients with confirmed COVID-19 (COVID-19 group) or suspected and ruled out COVID-19 (Non-COVID-19 group). Clinical evaluation and flow mediated vasodilation (FMD) were performed between the first 24-48 h of hospitalization. Patients were followed until death or discharge. RESULTS: We evaluated 98 patients (COVID-19 group) and 82 (Non-COVID-19 group), COVID-19 group remained hospitalized longer and more deaths occurred compared to the Non-COVID-19 group (p = 0.01; and p < 0.01). Patients in COVID-19 group also had a significantly greater reduction in both FMDmm and FMD% (p < 0.01 in both). We found that absolute FMD</=0.26 mm and relative FMD</=3.43% were the ideal cutoff point to predict mortality and longer hospital stay. In Kaplan Meyer's analysis patients had a high probability of death within a period of up to 10 days of hospitalization. CONCLUSION: Patients hospitalized for COVID-19 present endothelial vascular dysfunction early, remained hospitalized longer and had a higher number of deaths, when compared with patients without COVID-19. Twit Text FOAVip Endothelial function provides early prognostic information in patients with COVID-19: A cohort study ????Respir Med http://www.kidney.de/pget.php?&tw=1&pmid=34175806 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34175806 #FOAvip English Wikipedia <ref>{{Cite pmid|34175806}}</ref> Endothelial function provides early prognostic information in patients with COVID-19: A cohort study #MMPMID34175806 Oliveira MR; Back GD; da Luz Goulart C; Domingos BC; Arena R; Borghi-Silva A Respir Med 2021[Aug]; 185 (ä): 106469 PMID34175806show ga BACKGROUND: The prothrombotic phenotype and diffuse intravascular coagulation observed in COVID-19 reflect endothelial dysfunction, which is linked to blood flow delivery deficiencies and cardiovascular risk. Assessments of detect vascular deficiencies among newly diagnosed and hospitalized patients due to COVID-19 have yet to be determined. OBJECTIVE: To assess endothelial function characteristics in relation to length of hospitalization and mortality in patients diagnosed with COVID-19 and compare to patients without COVID-19. METHODS: A prospective observational study involving 180 patients with confirmed COVID-19 (COVID-19 group) or suspected and ruled out COVID-19 (Non-COVID-19 group). Clinical evaluation and flow mediated vasodilation (FMD) were performed between the first 24-48 h of hospitalization. Patients were followed until death or discharge. RESULTS: We evaluated 98 patients (COVID-19 group) and 82 (Non-COVID-19 group), COVID-19 group remained hospitalized longer and more deaths occurred compared to the Non-COVID-19 group (p = 0.01; and p < 0.01). Patients in COVID-19 group also had a significantly greater reduction in both FMDmm and FMD% (p < 0.01 in both). We found that absolute FMD |Brachial Artery/*physiopathology[MESH] |COVID-19/*epidemiology[MESH] |Cardiovascular Diseases/epidemiology/*physiopathology[MESH] |Comorbidity[MESH] |Endothelium, Vascular/*physiopathology[MESH] |Female[MESH] |Follow-Up Studies[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Prospective Studies[MESH] |Regional Blood Flow/*physiology[MESH] |SARS-CoV-2[MESH] |United States/epidemiology[MESH]Endothelial function provides early prognostic information in patients(epmc).pdf DeepDyve Pubget Overpricing