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10.1016/j.tracli.2021.06.004

http://scihub22266oqcxt.onion/10.1016/j.tracli.2021.06.004
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34175469!8225297!34175469
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suck abstract from ncbi


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pmid34175469      Transfus+Clin+Biol 2022 ; 29 (1): 89-91
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  • A novel scoring system for selecting the target patients of COVID-19 convalescent plasma therapy: A hypothesis #MMPMID34175469
  • Bansal N; Raturi M; Bansal Y; Singh P
  • Transfus Clin Biol 2022[Feb]; 29 (1): 89-91 PMID34175469show ga
  • The primary cause of mortality in patients of coronavirus disease 2019 (COVID-19) is the cytokine storm and not directly due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Therefore, it is being stressed by transfusion medicine specialists to use COVID-19 convalescent plasma (CCP) therapy early in the course of the disease, preferably within 72h of diagnosis. The authors herein, propose a scoring system for the rapid assessment of the patients who have tested positive for SARS-CoV-2. Therefore, a systematic approach may be followed where the patients are categorised into two groups, namely, the low-risk group [LRG; score<5] and the high-risk group [HRG; score >/= 5] based on this scoring system. Those classified as an HRG should be administered CCP therapy within 72h of a confirmed diagnosis of COVID-19 to neutralise the SARS-CoV-2 virus and prevent the occurrence of the cytokine storm. This in turn could help reduce the overall mortality in the recipients.
  • |*COVID-19/therapy[MESH]
  • |COVID-19 Serotherapy[MESH]
  • |Humans[MESH]
  • |Immunization, Passive[MESH]
  • |SARS-CoV-2[MESH]


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