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Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Transfus+Clin+Biol 2022 ; 29 (1): 89-91 Nephropedia Template TP
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A novel scoring system for selecting the target patients of COVID-19 convalescent plasma therapy: A hypothesis #MMPMID34175469
Bansal N; Raturi M; Bansal Y; Singh P
Transfus Clin Biol 2022[Feb]; 29 (1): 89-91 PMID34175469show ga
The primary cause of mortality in patients of coronavirus disease 2019 (COVID-19) is the cytokine storm and not directly due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Therefore, it is being stressed by transfusion medicine specialists to use COVID-19 convalescent plasma (CCP) therapy early in the course of the disease, preferably within 72h of diagnosis. The authors herein, propose a scoring system for the rapid assessment of the patients who have tested positive for SARS-CoV-2. Therefore, a systematic approach may be followed where the patients are categorised into two groups, namely, the low-risk group [LRG; score<5] and the high-risk group [HRG; score >/= 5] based on this scoring system. Those classified as an HRG should be administered CCP therapy within 72h of a confirmed diagnosis of COVID-19 to neutralise the SARS-CoV-2 virus and prevent the occurrence of the cytokine storm. This in turn could help reduce the overall mortality in the recipients.