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10.1097/MPG.0000000000003211

http://scihub22266oqcxt.onion/10.1097/MPG.0000000000003211
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34173793!8373382!34173793
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suck abstract from ncbi


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pmid34173793      J+Pediatr+Gastroenterol+Nutr 2021 ; 73 (3): 363-366
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  • High Seroconversion Rate Against Severe Acute Respiratory Syndrome Coronavirus 2 in Symptomatic Pediatric Inflammatory Bowel Disease Patients #MMPMID34173793
  • Ruan W; Nguyen H; Wyatt A; Ihekweazu F; Vartabedian BS; Karam L; Walsh S; Kellermayer R
  • J Pediatr Gastroenterol Nutr 2021[Sep]; 73 (3): 363-366 PMID34173793show ga
  • Understanding coronavirus disease 2019 (COVID-19) in pediatric inflammatory bowel disease (PIBD) is important. We describe a single-center cohort of COVID-19 PIBD patients where seroconversion against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was examined.Immunosuppressed PIBD patients at Texas Children's Hospital who tested positive for SARS-CoV-2 by nasopharyngeal reverse transcriptase polymerase chain reaction were included in the study. The clinical course of IBD, concurrent medications, COVID-19 related symptoms, SARS-CoV-2 testing date, and SARS-CoV-2 immunoglobulin G (IgG) antibody testing date and result were examined. Of 14 SARS-CoV-2 positive PIBD patients, 12 were tested for qualitative anti-SARS-CoV-2 IgG (seven with transient COVID-19 symptoms, five asymptomatic). All symptomatic (7/7) and 60% of asymptomatic (3/5) patients seroconverted. No patients required hospitalization attributed to COVID-19.High rates of COVID-19 seroconversion occurred in immunosuppressed and symptomatic PIBD patients. More research to evaluate the significance of COVID-19 seroconversion is needed.
  • |*COVID-19[MESH]
  • |*Inflammatory Bowel Diseases[MESH]
  • |Antibodies, Viral[MESH]
  • |COVID-19 Testing[MESH]
  • |Child[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2[MESH]


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