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10.1038/s41598-021-92740-9 http://scihub22266oqcxt.onion/10.1038/s41598-021-92740-9 34172783!8233421!34172783     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2021 ; 11 (1): 13308 Nephropedia Template TP {{tp|p=34172783|t=2021. Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19 |pdf=|usr=}}{{34172783}} gab.com Text Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19 JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=34172783 #FOAvip Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to the difficulty of obtaining biopsy specimens from infected individuals. In lieu of tissue samples, we measured cytokines, inflammatory markers, viral RNA, microbiome composition, and antibody responses in stool samples from a cohort of 44 hospitalized COVID-19 patients. SARS-CoV-2 RNA was detected in stool of 41% of patients and more frequently in patients with diarrhea. Patients who survived had lower fecal viral RNA than those who died. Strains isolated from stool and nasopharynx of an individual were the same. Compared to uninfected controls, COVID-19 patients had higher fecal levels of IL-8 and lower levels of fecal IL-10. Stool IL-23 was higher in patients with more severe COVID-19 disease, and we found evidence of intestinal virus-specific IgA responses associated with more severe disease. We provide evidence for an ongoing humeral immune response to SARS-CoV-2 in the gastrointestinal tract, but little evidence of overt inflammation. Twit Text FOAVip Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19 ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=34172783 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34172783 #FOAvip English Wikipedia <ref>{{Cite pmid|34172783}}</ref> Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19 #MMPMID34172783 Britton GJ; Chen-Liaw A; Cossarini F; Livanos AE; Spindler MP; Plitt T; Eggers J; Mogno I; Gonzalez-Reiche AS; Siu S; Tankelevich M; Grinspan LT; Dixon RE; Jha D; van de Guchte A; Khan Z; Martinez-Delgado G; Amanat F; Hoagland DA; tenOever BR; Dubinsky MC; Merad M; van Bakel H; Krammer F; Bongers G; Mehandru S; Faith JJ Sci Rep 2021[Jun]; 11 (1): 13308 PMID34172783show ga Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to the difficulty of obtaining biopsy specimens from infected individuals. In lieu of tissue samples, we measured cytokines, inflammatory markers, viral RNA, microbiome composition, and antibody responses in stool samples from a cohort of 44 hospitalized COVID-19 patients. SARS-CoV-2 RNA was detected in stool of 41% of patients and more frequently in patients with diarrhea. Patients who survived had lower fecal viral RNA than those who died. Strains isolated from stool and nasopharynx of an individual were the same. Compared to uninfected controls, COVID-19 patients had higher fecal levels of IL-8 and lower levels of fecal IL-10. Stool IL-23 was higher in patients with more severe COVID-19 disease, and we found evidence of intestinal virus-specific IgA responses associated with more severe disease. We provide evidence for an ongoing humeral immune response to SARS-CoV-2 in the gastrointestinal tract, but little evidence of overt inflammation. |*COVID-19/epidemiology/immunology[MESH] |*Feces/virology[MESH] |*Gastrointestinal Microbiome[MESH] |Aged[MESH] |Biomarkers/metabolism[MESH] |Cohort Studies[MESH] |Cytokines/metabolism[MESH] |Female[MESH] |Humans[MESH] |Immunoglobulin A/blood/immunology[MESH] |Male[MESH] |Middle Aged[MESH] |Nasopharynx/*virology[MESH] |New York City/epidemiology[MESH] |RNA, Viral/*isolation & purification[MESH]Limited intestinal inflammation despite diarrhea, fecal viral RNA and (epmc).pdf DeepDyve Pubget Overpricing