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10.1016/j.pharmthera.2021.107931 http://scihub22266oqcxt.onion/10.1016/j.pharmthera.2021.107931 34171328!8219947!34171328     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34171328&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmacol+Ther 2021 ; 228 (ä): 107931 Nephropedia Template TP {{tp|p=34171328|t=2021. Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions |pdf=|usr=}}{{34171328}} gab.com Text Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions JO: Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=34171328 #FOAvip Infections of the Coronavirus SARS-CoV-2 continue to spread around the globe, causing Coronavirus Disease (COVID)-19. Infected people are at risk of developing acute interstitial pneumonia, which can result in lethal complications, particularly in patients with pre-existing co-morbidities. Novel prophylactic and therapeutic interventions are urgently needed to limit the infection-associated health risk for the population and to contain the pandemic. Animal models are indispensable to assessing the efficacy and safety of potential new antivirals, vaccines, and other innovative therapies, such as nucleic acid agonists of innate immune sensing receptors. In this review, we provide an overview of the commonly used animal models to study SARS-CoV-2 and COVID-19, including a summary of their susceptibility to infection, the spectrum of symptoms elicited, and the potential for drug development in each model. We hope that this review will help researchers to decide on the right model organism to quickly address their specific scientific questions. Twit Text FOAVip Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions ????Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=34171328 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34171328 #FOAvip English Wikipedia <ref>{{Cite pmid|34171328}}</ref> Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions #MMPMID34171328 Renn M; Bartok E; Zillinger T; Hartmann G; Behrendt R Pharmacol Ther 2021[Dec]; 228 (ä): 107931 PMID34171328show ga Infections of the Coronavirus SARS-CoV-2 continue to spread around the globe, causing Coronavirus Disease (COVID)-19. Infected people are at risk of developing acute interstitial pneumonia, which can result in lethal complications, particularly in patients with pre-existing co-morbidities. Novel prophylactic and therapeutic interventions are urgently needed to limit the infection-associated health risk for the population and to contain the pandemic. Animal models are indispensable to assessing the efficacy and safety of potential new antivirals, vaccines, and other innovative therapies, such as nucleic acid agonists of innate immune sensing receptors. In this review, we provide an overview of the commonly used animal models to study SARS-CoV-2 and COVID-19, including a summary of their susceptibility to infection, the spectrum of symptoms elicited, and the potential for drug development in each model. We hope that this review will help researchers to decide on the right model organism to quickly address their specific scientific questions. |*COVID-19 Drug Treatment[MESH] |*Disease Models, Animal[MESH] |*Drug Development[MESH]Animal models of SARS-CoV-2 and COVID-19 for the development of prophy(epmc).pdf DeepDyve Pubget Overpricing