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10.1016/j.rceng.2021.04.002

http://scihub22266oqcxt.onion/10.1016/j.rceng.2021.04.002
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suck abstract from ncbi


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pmid34167924      Rev+Clin+Esp+(Barc) 2022 ; 222 (4): 229-232
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  • Meta-analysis evaluating the risk of respiratory tract infections and acute respiratory distress syndrome with glucagon-like peptide-1 receptor agonists in cardiovascular outcome trials: Useful implications for the COVID-19 pandemic #MMPMID34167924
  • Patoulias D; Boulmpou A; Imprialos K; Stavropoulos K; Papadopoulos C; Doumas M
  • Rev Clin Esp (Barc) 2022[Apr]; 222 (4): 229-232 PMID34167924show ga
  • Patients with type 2 diabetes mellitus (T2DM) are at increased risk for severe coronavirus disease 2019 (COVID-19) and related mortality. Glucagon-like peptide-1 receptor agonists (GLP-1-RAs) have significant cardiovascular and renal benefits for patients with T2DM and related comorbidities. Their anti-inflammatory properties could be beneficial in these patients. This work provides less-biased estimates regarding the risk for respiratory tract infections and acute respiratory distress syndrome by performing the first significant meta-analysis of cardiovascular outcome trials in the literature. Notably, GLP-1-RAs do not seem to increase the risk for respiratory tract infection, pneumonia, or acute respiratory distress syndrome in patients with T2DM and cardiovascular comorbidities.
  • |*COVID-19[MESH]
  • |*Cardiovascular Diseases/epidemiology/etiology[MESH]
  • |*Diabetes Mellitus, Type 2/chemically induced/complications/drug therapy[MESH]
  • |*Respiratory Distress Syndrome/drug therapy[MESH]
  • |Glucagon-Like Peptide 1[MESH]
  • |Glucagon-Like Peptide-1 Receptor/agonists[MESH]
  • |Humans[MESH]
  • |Hypoglycemic Agents/adverse effects[MESH]


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