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10.1016/j.cbi.2021.109567 http://scihub22266oqcxt.onion/10.1016/j.cbi.2021.109567 34166652!8217345!34166652     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Chem+Biol+Interact 2021 ; 345 (ä): 109567 Nephropedia Template TP {{tp|p=34166652|t=2021. TRP channels in COVID-19 disease: Potential targets for prevention and treatment |pdf=|usr=}}{{34166652}} gab.com Text TRP channels in COVID-19 disease: Potential targets for prevention and treatment JO: Chem Biol Interact http://www.kidney.de/pget.php?&tw=1&pmid=34166652 #FOAvip Coronavirus disease 2019 [COVID-19] is a global health threat caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins for entry: angiotensin-converting enzyme 2 [ACE2] and -membrane protease serine 2 [TMPRSS2]. Many patients complain from pneumonia, cough, fever, and gastrointestinal (GI) problems. Notably, different TRP channels are expressed in various tissues infected by SARS-CoV-2. TRP channels are cation channels that show a common architecture with high permeability to calcium [Ca(2+)] in most sub-families. Literature review shed light on the possible role of TRP channels in COVID-19 disease. TRP channels may take part in inflammation, pain, fever, anosmia, ageusia, respiratory, cardiovascular, GI and neurological complications related to COVID-19. Also, TRP channels could be the targets for many active compounds that showed effectiveness against SARS-CoV-2. Desensitization or blocking TRP channels by antibodies, aptamers, small molecules or venoms can be an option for COVID-19 prevention and future treatment. This review provides insights into the involvement of TRP channels in different symptoms and mechanisms of SARS-CoV-2 , potential treatments targeting these channels and highlights missing gaps in literature. Twit Text FOAVip TRP channels in COVID-19 disease: Potential targets for prevention and treatment ????Chem Biol Interact http://www.kidney.de/pget.php?&tw=1&pmid=34166652 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34166652 #FOAvip English Wikipedia <ref>{{Cite pmid|34166652}}</ref> TRP channels in COVID-19 disease: Potential targets for prevention and treatment #MMPMID34166652 Jaffal SM; Abbas MA Chem Biol Interact 2021[Aug]; 345 (ä): 109567 PMID34166652show ga Coronavirus disease 2019 [COVID-19] is a global health threat caused by severe acute respiratory syndrome coronavirus 2 [SARS-CoV2] that requires two proteins for entry: angiotensin-converting enzyme 2 [ACE2] and -membrane protease serine 2 [TMPRSS2]. Many patients complain from pneumonia, cough, fever, and gastrointestinal (GI) problems. Notably, different TRP channels are expressed in various tissues infected by SARS-CoV-2. TRP channels are cation channels that show a common architecture with high permeability to calcium [Ca(2+)] in most sub-families. Literature review shed light on the possible role of TRP channels in COVID-19 disease. TRP channels may take part in inflammation, pain, fever, anosmia, ageusia, respiratory, cardiovascular, GI and neurological complications related to COVID-19. Also, TRP channels could be the targets for many active compounds that showed effectiveness against SARS-CoV-2. Desensitization or blocking TRP channels by antibodies, aptamers, small molecules or venoms can be an option for COVID-19 prevention and future treatment. This review provides insights into the involvement of TRP channels in different symptoms and mechanisms of SARS-CoV-2 , potential treatments targeting these channels and highlights missing gaps in literature. |*COVID-19 Drug Treatment[MESH] |*Molecular Targeted Therapy[MESH] |COVID-19/metabolism/*prevention & control[MESH] |Humans[MESH]TRP channels in COVID-19 disease: Potential targets for prevention and(epmc).pdf DeepDyve Pubget Overpricing