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10.1093/pubmed/fdab215

http://scihub22266oqcxt.onion/10.1093/pubmed/fdab215
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34164680!ä!34164680

suck abstract from ncbi


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pmid34164680      J+Public+Health+(Oxf) 2022 ; 44 (1): e36-e41
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  • New method of screening for COVID-19 disease using sniffer dogs and scents from axillary sweat samples #MMPMID34164680
  • Sarkis R; Lichaa A; Mjaess G; Saliba M; Selman C; Lecoq-Julien C; Grandjean D; Jabbour NM
  • J Public Health (Oxf) 2022[Mar]; 44 (1): e36-e41 PMID34164680show ga
  • BACKGROUND: Early screening for COVID-19 is needed to limit the spread of the virus. The aim of this study is to test if the sniffer dogs can be successfully trained to identify subjects with COVID-19 for 'proof of concept' and 'non-inferiority' against PCR. We are calling this method, Dognosis (DN). METHODS: Four hundred and fifty-nine subjects were included, 256 (Group 'P') were known cases of COVID-19 (PCR positive, some with and some without symptoms) and 203 (Group 'C') were PCR negative and asymptomatic (control). Samples were obtained from the axillary sweat of each subject in a masked fashion. Two dogs trained to detect specific Volatile Organic Compounds for COVID-19 detection were used to test each sample. RESULTS: [DN] turned out positive (+) in all the cases that were PCR positive (100% sensitivity). On the other hand, [DN] turned positive (+) in an average of 12.5 cases (6.2%) that were initially PCR negative (apparent specificity of 93.8%). When the PCR was repeated, true specificity was 97.2%. These parameters varied in subgroups from 100% sensitivity and 99% specificity in symptomatic patients to 100% sensitivity and 93% specificity in asymptomatic patients. CONCLUSION: DN method shows high sensitivity and specificity in screening COVID-19 patients.
  • |*COVID-19/diagnosis/epidemiology[MESH]
  • |Animals[MESH]
  • |Dogs[MESH]
  • |Humans[MESH]
  • |Odorants[MESH]
  • |SARS-CoV-2[MESH]
  • |Sensitivity and Specificity[MESH]
  • |Sweat[MESH]


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