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10.3389/fcimb.2021.688007

http://scihub22266oqcxt.onion/10.3389/fcimb.2021.688007
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suck abstract from ncbi


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pmid34164347      Front+Cell+Infect+Microbiol 2021 ; 11 (ä): 688007
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  • Risk of Environmental Exposure to H7N9 Influenza Virus via Airborne and Surface Routes in a Live Poultry Market in Hebei, China #MMPMID34164347
  • Zhang C; Guo K; Cui H; Chen L; Zhang C; Wang X; Li J; Fu Y; Wang Z; Guo Z; Liu J; Dong S
  • Front Cell Infect Microbiol 2021[]; 11 (ä): 688007 PMID34164347show ga
  • Environmental transmission of viruses to humans has become an early warning for potential epidemic outbreaks, such as SARS-CoV-2 and influenza virus outbreaks. Recently, an H7N9 virus, A/environment/Hebei/621/2019 (H7N9), was isolated by environmental swabs from a live poultry market in Hebei, China. We found that this isolate could be transmitted by direct contact and aerosol in mammals. More importantly, after 5 passages in mice, the virus acquired two adaptive mutations, PB1-H115Q and B2-E627K, exhibiting increased virulence and aerosol transmissibility. These results suggest that this H7N9 virus might potentially be transmitted between humans through environmental or airborne routes.
  • |*Environmental Exposure[MESH]
  • |*Influenza A Virus, H7N9 Subtype[MESH]
  • |*Influenza in Birds/epidemiology[MESH]
  • |*Influenza, Human/epidemiology[MESH]
  • |Animals[MESH]
  • |China/epidemiology[MESH]
  • |Humans[MESH]
  • |Mice[MESH]


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