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10.1007/s12519-021-00431-2

http://scihub22266oqcxt.onion/10.1007/s12519-021-00431-2
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34160770!8219783!34160770
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suck abstract from ncbi


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pmid34160770      World+J+Pediatr 2021 ; 17 (3): 263-271
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  • Clinical characteristics of Kawasaki disease and concurrent pathogens during isolation in COVID-19 pandemic #MMPMID34160770
  • Ding YY; Ren Y; Qin J; Qian GH; Tang YJ; Chen Y; Li X; Xu L; Qiao CH; Sun L; Lv HT
  • World J Pediatr 2021[Jun]; 17 (3): 263-271 PMID34160770show ga
  • BACKGROUND: The aim of this study is to explore the characteristics of Kawasaki disease (KD) and concurrent pathogens due to a stay-at-home isolation policy during coronavirus disease 2019 (COVID-19) epidemic. METHODS: All patients with KD admitted between February and April in 2015-2020, were classified into before (group 1, in 2015-2019) and after (group 2, in 2020) isolation groups. A total of 4742 patients [with KD (n = 98) and non-KD (n = 4644)] referred to Mycoplasma pneumoniae (MP) and virus detection were analyzed in 2020. Clinical characteristics, laboratory data, and 13 pathogens were analyzed retrospectively. RESULTS: Group 2 had a significantly increased incidence of KD (0.11%) with 107 patients compared to that of group 1 (0.03%) with 493 patients. The comparisons of oral mucosal change, strawberry tongue, desquamation of the fingertips, cervical lymphadenopathy and neutrophil percentage decreased in group 2 compared to group 1. The infection rate of MP increased significantly in group 2 (34.7%) compared to group 1 (19.3%), while the positive rate of viruses decreased significantly in group 2 (5.3%) compared to group 1 (14.3%). In 2020, the positive rate of MP infection increased significantly in patients with KD compared to the increase in patients with non-KD. The infection rate of MP for younger children aged less than 3 years old was higher in group 2 than in group 1. CONCLUSION: Compared with the characteristics of KD from 2015 to 2019 years, the incidence of KD was increased in 2020 and was accompanied by a high incidence of MP infection, especially in younger children (less than 3 years old) during the isolation due to COVID-19 pandemic.
  • |*Physical Distancing[MESH]
  • |Adolescent[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Infant[MESH]
  • |Male[MESH]
  • |Mucocutaneous Lymph Node Syndrome/*epidemiology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Mycoplasma/*epidemiology[MESH]
  • |Respiratory Tract Infections/*epidemiology/*microbiology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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