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10.1177/17407745211024764 http://scihub22266oqcxt.onion/10.1177/17407745211024764 34154428!8479147!34154428     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Trials 2021 ; 18 (5): 615-621 Nephropedia Template TP {{tp|p=34154428|t=2021. Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom |pdf=|usr=}}{{34154428}} gab.com Text Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom JO: Clin Trials http://www.kidney.de/pget.php?&tw=1&pmid=34154428 #FOAvip The COVID-19 pandemic has resulted in unprecedented challenges for healthcare systems worldwide. It has also stimulated research in a wide range of areas including rapid diagnostics, novel therapeutics, use of technology to track patients and vaccine development. Here, we describe our experience of rapidly setting up and delivering a novel COVID-19 vaccine trial, using clinical and research staff and facilities in three National Health Service Trusts in Cambridgeshire, United Kingdom. We encountered and overcame a number of challenges including differences in organisational structures, research facilities available, staff experience and skills, information technology and communications infrastructure, and research training and assessment procedures. We overcame these by setting up a project team that included key members from all three organisations that met at least daily by teleconference. This group together worked to identify the best practices and procedures and to harmonise and cascade these to the wider trial team. This enabled us to set up the trial within 25 days and to recruit and vaccinate the participants within a further 23 days. The lessons learned from our experiences could be used to inform the conduct of clinical trials during a future infectious disease pandemic or public health emergency. Twit Text FOAVip Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom ????Clin Trials http://www.kidney.de/pget.php?&tw=1&pmid=34154428 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34154428 #FOAvip English Wikipedia <ref>{{Cite pmid|34154428}}</ref> Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom #MMPMID34154428 Torok ME; Underwood BR; Toshner M; Waddington C; Sidhom E; Sharrocks K; Bousfield R; Summers C; Saunders C; McIntyre Z; Morris H; Piper J; Calderon G; Dennis S; Assari T; de Rotrou AM; Shaw A; Bradley J; O'Brien J; Rintoul RC; Smith I; Bullmore E; Chatterjee K Clin Trials 2021[Oct]; 18 (5): 615-621 PMID34154428show ga The COVID-19 pandemic has resulted in unprecedented challenges for healthcare systems worldwide. It has also stimulated research in a wide range of areas including rapid diagnostics, novel therapeutics, use of technology to track patients and vaccine development. Here, we describe our experience of rapidly setting up and delivering a novel COVID-19 vaccine trial, using clinical and research staff and facilities in three National Health Service Trusts in Cambridgeshire, United Kingdom. We encountered and overcame a number of challenges including differences in organisational structures, research facilities available, staff experience and skills, information technology and communications infrastructure, and research training and assessment procedures. We overcame these by setting up a project team that included key members from all three organisations that met at least daily by teleconference. This group together worked to identify the best practices and procedures and to harmonise and cascade these to the wider trial team. This enabled us to set up the trial within 25 days and to recruit and vaccinate the participants within a further 23 days. The lessons learned from our experiences could be used to inform the conduct of clinical trials during a future infectious disease pandemic or public health emergency. |*COVID-19/prevention & control[MESH] |*Pandemics/prevention & control[MESH] |COVID-19 Vaccines/*therapeutic use[MESH] |Clinical Trials as Topic/organization & administration/*standards[MESH] |Humans[MESH] |State Medicine[MESH]Challenges and opportunities for conducting a vaccine trial during the(epmc).pdf DeepDyve Pubget Overpricing