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10.3389/fmolb.2021.671363 http://scihub22266oqcxt.onion/10.3389/fmolb.2021.671363 34150848!8212049!34150848     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Mol+Biosci 2021 ; 8 (ä): 671363 Nephropedia Template TP {{tp|p=34150848|t=2021. Sex-Related Overactivation of NLRP3 Inflammasome Increases Lethality of the Male COVID-19 Patients |pdf=|usr=}}{{34150848}} gab.com Text Sex-Related Overactivation of NLRP3 Inflammasome Increases Lethality of the Male COVID-19 Patients JO: Front Mol Biosci http://www.kidney.de/pget.php?&tw=1&pmid=34150848 #FOAvip The COVID-19 pandemic, caused by SARS-CoV-2 infection, remains a dramatic threat to human life and economic well-being worldwide. Significant heterogeneity in the severity of disease was observed for patients infected with SARS-CoV-2 ranging from asymptomatic to severe cases. Moreover, male patients had a higher probability of suffering from high mortality and severe symptoms linked to cytokine storm and excessive inflammation. The NLRP3 inflammasome is presumably critical to this process. Sex differences may directly affect the activation of NLRP3 inflammasome, impacting the severity of observed COVID-19 symptoms. To elucidate the potential mechanisms underlying sex based differences in NLRP3 activation during SARS-CoV-2 infection, this review summarizes the reported mechanisms and identifies potential therapeutic targets. Twit Text FOAVip Sex-Related Overactivation of NLRP3 Inflammasome Increases Lethality of the Male COVID-19 Patients ????Front Mol Biosci http://www.kidney.de/pget.php?&tw=1&pmid=34150848 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34150848 #FOAvip English Wikipedia <ref>{{Cite pmid|34150848}}</ref> Sex-Related Overactivation of NLRP3 Inflammasome Increases Lethality of the Male COVID-19 Patients #MMPMID34150848 Zhang H; Tang Y; Tao J Front Mol Biosci 2021[]; 8 (ä): 671363 PMID34150848show ga The COVID-19 pandemic, caused by SARS-CoV-2 infection, remains a dramatic threat to human life and economic well-being worldwide. Significant heterogeneity in the severity of disease was observed for patients infected with SARS-CoV-2 ranging from asymptomatic to severe cases. Moreover, male patients had a higher probability of suffering from high mortality and severe symptoms linked to cytokine storm and excessive inflammation. The NLRP3 inflammasome is presumably critical to this process. Sex differences may directly affect the activation of NLRP3 inflammasome, impacting the severity of observed COVID-19 symptoms. To elucidate the potential mechanisms underlying sex based differences in NLRP3 activation during SARS-CoV-2 infection, this review summarizes the reported mechanisms and identifies potential therapeutic targets. äSex-Related Overactivation of NLRP3 Inflammasome Increases Lethality o(epmc).pdf DeepDyve Pubget Overpricing