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10.1016/j.bios.2021.113423 http://scihub22266oqcxt.onion/10.1016/j.bios.2021.113423 34147946!ä!34147946 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biosens+Bioelectron 2021 ; 190 (ä): 113423 Nephropedia Template TP {{tp|p=34147946|t=2021. Highly sensitive wide-range target fluorescence biosensors of high-emittance metasurfaces |pdf=|usr=}}{{34147946}} gab.com Text Highly sensitive wide-range target fluorescence biosensors of high-emittance metasurfaces JO: Biosens Bioelectron http://www.kidney.de/pget.php?&tw=1&pmid=34147946 #FOAvip We demonstrate highly sensitive fluorescence (FL) biosensors made of plasmon-photon-hybrid high-emittance metasurfaces, which are hybrid structures composed of perforated silicon waveguides and stacked complementary (SC) gold nanostructures. The SC metasurfaces are applicable to a wide range of targets from antibodies to nucleic acids. As a test bed, a representative antibody of immunoglobulin G is immobilized on the metasurfaces through microfluidic paths and then is directly detected in a scaled manner even at a very low concentration of 5 pg mL(-1), i.e., 34 fM. Moreover, a cancer marker of p53 antibody is indirectly detected on the SC metasurfaces at a low concentration of 50 pg mL(-1), which is significantly lower than the medical diagnosis criterion of a few ng mL(-1). Furthermore, single-strand DNAs that are oligonucleotides and complementary to SARS-CoV-2 RNA are detected with 1 h immobilization time in the range of fmol mL(-1) in a scaled manner. These experimental results indicate that the present FL metasurface sensors function efficiently as biosensors for a wide range of biomarkers. Twit Text FOAVip Highly sensitive wide-range target fluorescence biosensors of high-emittance metasurfaces ????Biosens Bioelectron http://www.kidney.de/pget.php?&tw=1&pmid=34147946 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34147946 #FOAvip English Wikipedia <ref>{{Cite pmid|34147946}}</ref> Highly sensitive wide-range target fluorescence biosensors of high-emittance metasurfaces #MMPMID34147946 Iwanaga M Biosens Bioelectron 2021[Oct]; 190 (ä): 113423 PMID34147946show ga We demonstrate highly sensitive fluorescence (FL) biosensors made of plasmon-photon-hybrid high-emittance metasurfaces, which are hybrid structures composed of perforated silicon waveguides and stacked complementary (SC) gold nanostructures. The SC metasurfaces are applicable to a wide range of targets from antibodies to nucleic acids. As a test bed, a representative antibody of immunoglobulin G is immobilized on the metasurfaces through microfluidic paths and then is directly detected in a scaled manner even at a very low concentration of 5 pg mL(-1), i.e., 34 fM. Moreover, a cancer marker of p53 antibody is indirectly detected on the SC metasurfaces at a low concentration of 50 pg mL(-1), which is significantly lower than the medical diagnosis criterion of a few ng mL(-1). Furthermore, single-strand DNAs that are oligonucleotides and complementary to SARS-CoV-2 RNA are detected with 1 h immobilization time in the range of fmol mL(-1) in a scaled manner. These experimental results indicate that the present FL metasurface sensors function efficiently as biosensors for a wide range of biomarkers. |*Biosensing Techniques[MESH] |*COVID-19[MESH] |Gold[MESH] |Humans[MESH] |RNA, Viral[MESH]Highly sensitive wide-range target fluorescence biosensors of high-emi(epmc).pdf DeepDyve Pubget Overpricing