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10.1016/j.ijid.2021.06.027 http://scihub22266oqcxt.onion/10.1016/j.ijid.2021.06.027 34147667!8240518!34147667     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Infect+Dis 2021 ; 109 (ä): 50-53 Nephropedia Template TP {{tp|p=34147667|t=2021. Detection of SARS-CoV-2 variants requires urgent global coordination |pdf=|usr=}}{{34147667}} gab.com Text Detection of SARS-CoV-2 variants requires urgent global coordination JO: Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34147667 #FOAvip OBJECTIVES: To assess the efforts deployed by different nations and territories in sequencing SARS-CoV-2 isolates, thus enabling detection of variants, known and novel, of concern. METHODS: The sources of over one million full genome sequences of SARS-CoV-2 virus available in the COVID-19 virus Mutation Tracker (CovMT) were analyzed to determine the number of variants in the RBD region of the genome determining infectivity detected in the various nations and territories. RESULTS: The number of detected variants increased as the square root of sequencing effort by nations. Eight nations have contributed 79% of all SARS-CoV-2 isolates that have been sequenced, with two-thirds of all unique variants, adding to 1118 RBD variants, reported by five nations. The median number of sequenced isolates required to detect, on average, one novel RBD variant is 24.05, which is a threshold achieved by 70 nations. CONCLUSIONS: Many developing nations have not contributed any sequences due to lack of capacity. This poses a risk of dangerous virus variants in these under-sampled regions spreading globally before being detected. A collaborative program to sequence SARS-CoV-2 isolates, and other pathogens of concern, is needed to monitor, track, and control the pandemic. Twit Text FOAVip Detection of SARS-CoV-2 variants requires urgent global coordination ????Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34147667 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34147667 #FOAvip English Wikipedia <ref>{{Cite pmid|34147667}}</ref> Detection of SARS-CoV-2 variants requires urgent global coordination #MMPMID34147667 Duarte CM; Jamil T; Gojobori T; Alam I Int J Infect Dis 2021[Aug]; 109 (ä): 50-53 PMID34147667show ga OBJECTIVES: To assess the efforts deployed by different nations and territories in sequencing SARS-CoV-2 isolates, thus enabling detection of variants, known and novel, of concern. METHODS: The sources of over one million full genome sequences of SARS-CoV-2 virus available in the COVID-19 virus Mutation Tracker (CovMT) were analyzed to determine the number of variants in the RBD region of the genome determining infectivity detected in the various nations and territories. RESULTS: The number of detected variants increased as the square root of sequencing effort by nations. Eight nations have contributed 79% of all SARS-CoV-2 isolates that have been sequenced, with two-thirds of all unique variants, adding to 1118 RBD variants, reported by five nations. The median number of sequenced isolates required to detect, on average, one novel RBD variant is 24.05, which is a threshold achieved by 70 nations. CONCLUSIONS: Many developing nations have not contributed any sequences due to lack of capacity. This poses a risk of dangerous virus variants in these under-sampled regions spreading globally before being detected. A collaborative program to sequence SARS-CoV-2 isolates, and other pathogens of concern, is needed to monitor, track, and control the pandemic. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Humans[MESH] |Mutation[MESH]Detection of SARS-CoV-2 variants requires urgent global coordination (epmc).pdf DeepDyve Pubget Overpricing