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10.1016/j.pep.2021.105930

http://scihub22266oqcxt.onion/10.1016/j.pep.2021.105930
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34147604!ä!34147604

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suck abstract from ncbi


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pmid34147604      Protein+Expr+Purif 2021 ; 186 (ä): 105930
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  • Evaluating a new mixed-mode resin Diamond MMC Mustang using Capto MMC ImpRes as a benchmark #MMPMID34147604
  • Zhang S; Wan Y; Duan J; Li Y
  • Protein Expr Purif 2021[Oct]; 186 (ä): 105930 PMID34147604show ga
  • Diamond MMC Mustang is a relatively new mixed-mode resin, which mediates both cation exchange and hydrophobic interactions. In this work, we evaluated this resin using Cytiva's Capto MMC ImpRes, a well-established mixed-mode resin with similar properties, as a benchmark. The data suggest that in comparison with Capto MMC ImpRes, Diamond MMC Mustang exhibits comparable binding capacity and resolution. In addition, the resin under evaluation shows good lot-to-lot consistency. The information provided in this study allows users to have additional options when selecting mixed-mode resin for intermediate purification or final polishing, which is favourable especially at the present time when the supply chains of many manufacturers are negatively impacted by the coronavirus pandemic.
  • |Animals[MESH]
  • |Antibodies, Bispecific/immunology/*isolation & purification[MESH]
  • |Benchmarking[MESH]
  • |CHO Cells[MESH]
  • |Chromatography, Affinity/instrumentation/*methods[MESH]
  • |Cricetulus[MESH]


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