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10.1172/JCI151178

http://scihub22266oqcxt.onion/10.1172/JCI151178
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34143755!8279579!34143755
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suck abstract from ncbi


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pmid34143755      J+Clin+Invest 2021 ; 131 (14): ä
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  • Interpreting and addressing suboptimal immune responses after COVID-19 vaccination in solid-organ transplant recipients #MMPMID34143755
  • Stock PG; Henrich TJ; Segev DL; Werbel WA
  • J Clin Invest 2021[Jul]; 131 (14): ä PMID34143755show ga
  • Transplant recipients were excluded from the initial clinical trials determining safety and efficacy of the landmark COVID-19 vaccines. Further, there is increasing evidence that immunosuppressed transplant recipients have a blunted antibody response to COVID-19 vaccination. In a concerning report by Sattler et al. in this issue of the JCI, kidney transplant recipients not only lacked a humoral response following two doses of Pfizer BNT162b2, but also displayed substantial impairment of the cellular response to SARS-CoV-2 antigens. This Commentary addresses potential strategies for transplant providers to evaluate and augment vaccine immunogenicity given the likelihood that COVID-19 will remain a world-wide threat to the health of transplant recipients.
  • |*COVID-19[MESH]
  • |*Organ Transplantation[MESH]
  • |Antibody Formation[MESH]
  • |BNT162 Vaccine[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2[MESH]
  • |Transplant Recipients[MESH]


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