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10.1002/2211-5463.13232 http://scihub22266oqcxt.onion/10.1002/2211-5463.13232 34137203!8329949!34137203     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34137203&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       FEBS+Open+Bio 2021 ; 11 (8): 2266-2272 Nephropedia Template TP {{tp|p=34137203|t=2021. Pulmonary ACE2 expression in neonatal and adult rats |pdf=|usr=}}{{34137203}} gab.com Text Pulmonary ACE2 expression in neonatal and adult rats JO: FEBS Open Bio http://www.kidney.de/pget.php?&tw=1&pmid=34137203 #FOAvip Children show a distinct presentation of COVID-19, characterized by a lower incidence and mild phenotype, but the reason for this is still unknown. The angiotensin-converting enzyme 2 (ACE2) functions as the primary cell entry receptor for Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is thought to cause distinct clinical features between children and old people. The primary purpose of this study was to determine whether differences exist in the level of expression and distribution of ACE2 between neonatal and adult rat lungs. The lung tissues from rats of various ages were used to investigate the expression patterns of ACE2. Western blot, immunohistochemistry, and immunofluorescence were used to quantify or identify the localization of ACE2 in rat lungs. ACE2 was homogenously expressed in fewer alveolar type II (AT2) cells in the neonatal lung, with no polarization to the alveolar space and additional expression in pulmonary endothelium when compared to adult rat lungs. These findings suggest that the patterns of ACE2 distribution and cellular localization in rat lungs change with age. Twit Text FOAVip Pulmonary ACE2 expression in neonatal and adult rats ????FEBS Open Bio http://www.kidney.de/pget.php?&tw=1&pmid=34137203 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34137203 #FOAvip English Wikipedia <ref>{{Cite pmid|34137203}}</ref> Pulmonary ACE2 expression in neonatal and adult rats #MMPMID34137203 Zhao D; Chen X; Han D; Zhong J; Zhang SE; Yang C FEBS Open Bio 2021[Aug]; 11 (8): 2266-2272 PMID34137203show ga Children show a distinct presentation of COVID-19, characterized by a lower incidence and mild phenotype, but the reason for this is still unknown. The angiotensin-converting enzyme 2 (ACE2) functions as the primary cell entry receptor for Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is thought to cause distinct clinical features between children and old people. The primary purpose of this study was to determine whether differences exist in the level of expression and distribution of ACE2 between neonatal and adult rat lungs. The lung tissues from rats of various ages were used to investigate the expression patterns of ACE2. Western blot, immunohistochemistry, and immunofluorescence were used to quantify or identify the localization of ACE2 in rat lungs. ACE2 was homogenously expressed in fewer alveolar type II (AT2) cells in the neonatal lung, with no polarization to the alveolar space and additional expression in pulmonary endothelium when compared to adult rat lungs. These findings suggest that the patterns of ACE2 distribution and cellular localization in rat lungs change with age. ?Pulmonary ACE2 expression in neonatal and adult rats (epmc).pdf DeepDyve Pubget Overpricing