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10.1097/j.pbj.0000000000000132 http://scihub22266oqcxt.onion/10.1097/j.pbj.0000000000000132 34136717!8202634!34136717     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Porto+Biomed+J 2021 ; 6 (3): e132 Nephropedia Template TP {{tp|p=34136717|t=2021. Old drugs for a new indication: a review of chloroquine and analogue in COVID-19 treatment |pdf=|usr=}}{{34136717}} gab.com Text Old drugs for a new indication: a review of chloroquine and analogue in COVID-19 treatment JO: Porto Biomed J http://www.kidney.de/pget.php?&tw=1&pmid=34136717 #FOAvip As an innovative therapeutic strategy, drug repurposing affords old, approved, and already established drugs a chance at new indications. In the wake of the COVID-19 pandemic and the accompanied urgency for a lasting treatment, drug repurposing has come in handy to stem the debilitating effects of the disease. Among other therapeutic options currently in clinical trials, chloroquine (CQ) and the hydroxylated analogue, hydroxychloroquine (HCQ) have been frontline therapeutic options in most formal and informal clinical settings with varying degrees of efficacy against this life-threatening disease. Their status in randomized clinical trials is related to the biochemical and pharmacological profiles as validated by in vitro, in vivo and case studies. With the aim to bear a balance for their use in the long run, this review not only synopsizes findings from recent studies on the degrees of efficacy and roles of CQ/HCQ as potential anti-COVID-19 agents but also highlights our perspectives for their consideration in rational drug repositioning and use. Twit Text FOAVip Old drugs for a new indication: a review of chloroquine and analogue in COVID-19 treatment ????Porto Biomed J http://www.kidney.de/pget.php?&tw=1&pmid=34136717 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34136717 #FOAvip English Wikipedia <ref>{{Cite pmid|34136717}}</ref> Old drugs for a new indication: a review of chloroquine and analogue in COVID-19 treatment #MMPMID34136717 Ehianeta TS; Akinyeye RO; Orege JI; Ejeromedoghene O; Adebule AP; Okonkwo BO Porto Biomed J 2021[May]; 6 (3): e132 PMID34136717show ga As an innovative therapeutic strategy, drug repurposing affords old, approved, and already established drugs a chance at new indications. In the wake of the COVID-19 pandemic and the accompanied urgency for a lasting treatment, drug repurposing has come in handy to stem the debilitating effects of the disease. Among other therapeutic options currently in clinical trials, chloroquine (CQ) and the hydroxylated analogue, hydroxychloroquine (HCQ) have been frontline therapeutic options in most formal and informal clinical settings with varying degrees of efficacy against this life-threatening disease. Their status in randomized clinical trials is related to the biochemical and pharmacological profiles as validated by in vitro, in vivo and case studies. With the aim to bear a balance for their use in the long run, this review not only synopsizes findings from recent studies on the degrees of efficacy and roles of CQ/HCQ as potential anti-COVID-19 agents but also highlights our perspectives for their consideration in rational drug repositioning and use. äOld drugs for a new indication: a review of chloroquine and analogue i(epmc).pdf DeepDyve Pubget Overpricing