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10.1017/S1047951121002614

http://scihub22266oqcxt.onion/10.1017/S1047951121002614
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34134808!8280460!34134808
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suck abstract from ncbi


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pmid34134808      Cardiol+Young 2022 ; 32 (1): 165-168
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  • Cardiac manifestations and short-term outcomes of multisystem inflammatory syndrome in Middle Eastern children during the COVID-19 pandemic: a case series #MMPMID34134808
  • Tannoury TE; Bulbul ZR; Bitar FF
  • Cardiol Young 2022[Jan]; 32 (1): 165-168 PMID34134808show ga
  • We herein report on a series of four patients presented to our tertiary care centre with features of multisystem inflammatory syndrome in children and cardiac involvement. Two of our patients had recent exposure to a COVID-19-positive patient, one had recent documented infection, and another had no known positive contact. All the patients were tested positive for severe acute respiratory syndrome coronavirus 2 immunoglobulin G antibody at the time of presentation. All of them fulfilled the diagnostic criteria according to the World Health Organization Centers for Disease Control or the British guidelines for MIS-C (fever for >/=3 days, multisystem involvement (at least two), elevated markers of inflammation, and no other alternative diagnosis).Cardiac involvement was variable ranging from isolated ectasia of the coronary arteries to full-blown pancarditis such as severe biventricular dysfunction, multi-valvar involvement, and pericardial effusion.All our patients received intravenous immunoglobulin (2 g/kg), methylprednisolone, and aspirin and some required inotropic support and ICU admission.Remarkably, all our patients showed significant improvement in their cardiac disease within a few days as evident on serial echocardiographic evaluation. However, we stress the need for long-term follow-up as one of our patients demonstrated mild LV myocardial scarring as evident by gadolinium late enhancement on a cardiac MRI.
  • |*COVID-19/complications[MESH]
  • |*Pericardial Effusion[MESH]
  • |Child[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2[MESH]


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