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10.1186/s12884-021-03928-w

http://scihub22266oqcxt.onion/10.1186/s12884-021-03928-w
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34134652!8207493!34134652
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suck abstract from ncbi


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pmid34134652      BMC+Pregnancy+Childbirth 2021 ; 21 (1): 427
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  • Euglycaemic ketoacidosis in pregnant women with COVID-19: two case reports #MMPMID34134652
  • Pikovsky M; Tan MY; Ahmed A; Sykes L; Agha-Jaffar R; Yu CKH
  • BMC Pregnancy Childbirth 2021[Jun]; 21 (1): 427 PMID34134652show ga
  • BACKGROUND: Euglycaemic ketoacidosis (EKA) is an infrequent but serious condition which usually follows a period of starvation, severe vomiting or illness in individuals with or without diabetes. Ketoacidosis is associated with materno-fetal morbidity and mortality necessitating prompt diagnosis and management. Physiological increases in insulin resistance render pregnancy a diabetogenic state with increased susceptibility to ketosis. COVID-19 is associated with worse clinical outcomes in patients with diabetes and is an independent risk factor for ketoacidosis in normoglycaemic individuals. CASE PRESENTATIONS: We describe two cases of SARS-CoV-2 positive pregnant women presenting with normoglycaemic metabolic ketoacidosis. Both cases were associated with maternal and fetal compromise, requiring aggressive fluid and insulin resuscitation and early delivery. CONCLUSION: We discuss possible physiology and propose a management strategy for euglycaemic ketoacidosis in pregnancy.
  • |COVID-19/complications/*diagnosis[MESH]
  • |Female[MESH]
  • |Fluid Therapy/methods[MESH]
  • |Humans[MESH]
  • |Insulin Resistance[MESH]
  • |Ketosis/complications/*diagnosis/therapy[MESH]
  • |Maternal-Fetal Exchange[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications/*diagnosis/therapy[MESH]
  • |SARS-CoV-2[MESH]


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