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10.1093/ndt/gfab200 http://scihub22266oqcxt.onion/10.1093/ndt/gfab200 34132811!8394823!34132811     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nephrol+Dial+Transplant 2021 ; 36 (11): 2094-2105 Nephropedia Template TP {{tp|p=34132811|t=2021. COVID-19-related mortality in kidney transplant and haemodialysis patients: a comparative, prospective registry-based study |pdf=|usr=}}{{34132811}} gab.com Text COVID-19-related mortality in kidney transplant and haemodialysis patients: a comparative, prospective registry-based study JO: Nephrol Dial Transplant http://www.kidney.de/pget.php?&tw=1&pmid=34132811 #FOAvip BACKGROUND: Coronavirus disease 2019 (COVID-19) has exposed haemodialysis (HD) patients and kidney transplant (KT) recipients to an unprecedented life-threatening infectious disease, raising concerns about kidney replacement therapy (KRT) strategy during the pandemic. This study investigated the association of the type of KRT with COVID-19 severity, adjusting for differences in individual characteristics. METHODS: Data on KT recipients and HD patients diagnosed with COVID-19 between 1 February 2020 and 1 December 2020 were retrieved from the European Renal Association COVID-19 Database. Cox regression models adjusted for age, sex, frailty and comorbidities were used to estimate hazard ratios (HRs) for 28-day mortality risk in all patients and in the subsets that were tested because of symptoms. RESULTS: A total of 1670 patients (496 functional KT and 1174 HD) were included; 16.9% of KT and 23.9% of HD patients died within 28 days of presentation. The unadjusted 28-day mortality risk was 33% lower in KT recipients compared with HD patients HR 0.67 [95% confidence interval (CI) 0.52-0.85]. In a fully adjusted model, the risk was 78% higher in KT recipients [HR 1.78 (95% CI 1.22-2.61)] compared with HD patients. This association was similar in patients tested because of symptoms [fully adjusted model HR 2.00 (95% CI 1.31-3.06)]. This risk was dramatically increased during the first post-transplant year. Results were similar for other endpoints (e.g. hospitalization, intensive care unit admission and mortality >28 days) and across subgroups. CONCLUSIONS: KT recipients had a greater risk of a more severe course of COVID-19 compared with HD patients, therefore they require specific infection mitigation strategies. Twit Text FOAVip COVID-19-related mortality in kidney transplant and haemodialysis patients: a comparative, prospective registry-based study ????Nephrol Dial Transplant http://www.kidney.de/pget.php?&tw=1&pmid=34132811 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34132811 #FOAvip English Wikipedia <ref>{{Cite pmid|34132811}}</ref> COVID-19-related mortality in kidney transplant and haemodialysis patients: a comparative, prospective registry-based study #MMPMID34132811 Goffin E; Candellier A; Vart P; Noordzij M; Arnol M; Covic A; Lentini P; Malik S; Reichert LJ; Sever MS; Watschinger B; Jager KJ; Gansevoort RT Nephrol Dial Transplant 2021[Nov]; 36 (11): 2094-2105 PMID34132811show ga BACKGROUND: Coronavirus disease 2019 (COVID-19) has exposed haemodialysis (HD) patients and kidney transplant (KT) recipients to an unprecedented life-threatening infectious disease, raising concerns about kidney replacement therapy (KRT) strategy during the pandemic. This study investigated the association of the type of KRT with COVID-19 severity, adjusting for differences in individual characteristics. METHODS: Data on KT recipients and HD patients diagnosed with COVID-19 between 1 February 2020 and 1 December 2020 were retrieved from the European Renal Association COVID-19 Database. Cox regression models adjusted for age, sex, frailty and comorbidities were used to estimate hazard ratios (HRs) for 28-day mortality risk in all patients and in the subsets that were tested because of symptoms. RESULTS: A total of 1670 patients (496 functional KT and 1174 HD) were included; 16.9% of KT and 23.9% of HD patients died within 28 days of presentation. The unadjusted 28-day mortality risk was 33% lower in KT recipients compared with HD patients HR 0.67 [95% confidence interval (CI) 0.52-0.85]. In a fully adjusted model, the risk was 78% higher in KT recipients [HR 1.78 (95% CI 1.22-2.61)] compared with HD patients. This association was similar in patients tested because of symptoms [fully adjusted model HR 2.00 (95% CI 1.31-3.06)]. This risk was dramatically increased during the first post-transplant year. Results were similar for other endpoints (e.g. hospitalization, intensive care unit admission and mortality >28 days) and across subgroups. CONCLUSIONS: KT recipients had a greater risk of a more severe course of COVID-19 compared with HD patients, therefore they require specific infection mitigation strategies. |*COVID-19[MESH] |*Kidney Failure, Chronic/therapy[MESH] |*Kidney Transplantation/adverse effects[MESH] |Humans[MESH] |Registries[MESH] |Renal Dialysis[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH]COVID-19-related mortality in kidney transplant and haemodialysis pati(epmc).pdf DeepDyve Pubget Overpricing