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10.12788/jhm.3594

http://scihub22266oqcxt.onion/10.12788/jhm.3594
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34129486!ä!34129486

suck abstract from ncbi


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pmid34129486      J+Hosp+Med 2021 ; 16 (6): 349-352
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  • Gender Differences in the Presentation and Outcomes of Hospitalized Patients With COVID-19 #MMPMID34129486
  • Biole C; Bianco M; Nunez-Gil IJ; Cerrato E; Spirito A; Roubin SR; Viana-Llamas MC; Gonzalez A; Castro-Mejia AF; Eid CM; Fernandez-Perez C; Uribarri A; Alfonso-Rodriguez E; Ugo F; Guerra F; Feltes G; Akin I; Fernandez-Rozas I; Blasco-Angulo N; Huang J; Aguado MG; Pepe M; Romero R; Becerra-Munoz VM; Estrada V; Macaya C
  • J Hosp Med 2021[Jun]; 16 (6): 349-352 PMID34129486show ga
  • Gender-related differences in COVID-19 clinical presentation, disease progression, and mortality have not been adequately explored. We analyzed the clinical profile, presentation, treatments, and outcomes of patients according to gender in the HOPE-COVID-19 International Registry. Among 2,798 enrolled patients, 1,111 were women (39.7%). Male patients had a higher prevalence of cardiovascular risk factors and more comorbidities at baseline. After propensity score matching, 876 men and 876 women were selected. Male patients more often reported fever, whereas female patients more often reported vomiting, diarrhea, and hyposmia/anosmia. Laboratory tests in men presented alterations consistent with a more severe COVID-19 infection (eg, significantly higher C-reactive protein, troponin, transaminases, lymphocytopenia, thrombocytopenia, and ferritin). Systemic inflammatory response syndrome, bilateral pneumonia, respiratory insufficiency, and renal failure were significantly more frequent in men. Men more often required pronation, corticosteroids, and tocilizumab administration. A significantly higher 30-day mortality was observed in men vs women (23.4% vs 19.2%; P = .039). Trial Numbers: NCT04334291/EUPAS34399.
  • |*Hospitalization[MESH]
  • |*Sex Factors[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*diagnosis/mortality[MESH]
  • |Cohort Studies[MESH]
  • |Comorbidity[MESH]
  • |Disease Progression[MESH]
  • |Female[MESH]
  • |Heart Disease Risk Factors[MESH]
  • |Humans[MESH]
  • |Male[MESH]


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