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10.1093/jpids/piab035 http://scihub22266oqcxt.onion/10.1093/jpids/piab035 34129032!8344587!34129032     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34129032&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Pediatric+Infect+Dis+Soc 2021 ; 10 (7): 757-765 Nephropedia Template TP {{tp|p=34129032|t=2021. COVID-19 in a Subset of Hospitalized Children in Israel |pdf=|usr=}}{{34129032}} gab.com Text COVID-19 in a Subset of Hospitalized Children in Israel JO: J Pediatric Infect Dis Soc http://www.kidney.de/pget.php?&tw=1&pmid=34129032 #FOAvip BACKGROUND: Most pediatric coronavirus disease 2019 (COVID-19) is mild. We assessed nationally severe COVID-19, including pediatric inflammatory multisystem syndrome (PIMS), in hospitalized children. METHODS: An ongoing, prospective, national surveillance was conducted from March 2020 through March 2021, at 20 hospitals treating children <18 years across Israel (~75% of Israeli hospitals). RESULTS: Overall, 1007 cases (439 outpatients and 568 hospitalized) identified represent 0.35% of pediatric COVID-19 nationwide (n = 291 628). Of hospitalized cases, 464 (82%), 48 (8%), and 56 (10%) had mild, moderate/severe, and PIMS disease, respectively. The mean +/- SD age was 5.6 +/- 6.4 years. In mild, moderate/severe, and PIMS disease, 55%, 23%, and 4% of patients were <1 year old, respectively. Obesity was reported in 1%, 4%, and 13% of patients, respectively (P < .001). The most common symptom was fever in 67%, 60%, and 100%, respectively, whereas respiratory symptoms were documented in 33%, 41%, and 38% of patients, respectively. Lymphopenia was recorded in 25%, 60%, and 86% of cases, respectively. PIMS diagnosis was mainly serology-based (in 59%). Gastrointestinal symptoms, cardiovascular involvement, rash, and conjunctivitis were noted in 82%, 61%, 57%, and 34% of PIMS episodes, respectively. Elevated C-reactive protein (100%), ferritin, troponin, D-dimer, low albumin, and thrombocytopenia were common in PIMS. Echocardiography revealed pathological findings in 33% of patients. PIMS mainstay treatment included corticosteroids (77%) and intravenous immunoglobulin (53%). No mortality was recorded. CONCLUSIONS: At a national level, pediatric COVID-19 is mild, even in hospitalized cases, with only a third presenting with respiratory involvement. PIMS is rare, but necessitates a high index of suspicion, and with suitable treatment prognosis is favorable. Twit Text FOAVip COVID-19 in a Subset of Hospitalized Children in Israel ????J Pediatric Infect Dis Soc http://www.kidney.de/pget.php?&tw=1&pmid=34129032 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34129032 #FOAvip English Wikipedia <ref>{{Cite pmid|34129032}}</ref> COVID-19 in a Subset of Hospitalized Children in Israel #MMPMID34129032 Ben-Shimol S; Livni G; Megged O; Greenberg D; Danino D; Youngster I; Shachor-Meyouhas Y; Dabaja-Younis H; Scheuerman O; Mor M; Somekh E; Yakub Hanna H; Givon-Lavi N; Guri A; Leibovitz E; Alkan Y; Grupel D; Rubinstein U; Steinberg Ben Zeev Z; Bamberger E; Asher Kuperman A; Grisaru-Soen G; Tasher D; Gottesman G; Glikman D; Stein M J Pediatric Infect Dis Soc 2021[Aug]; 10 (7): 757-765 PMID34129032show ga BACKGROUND: Most pediatric coronavirus disease 2019 (COVID-19) is mild. We assessed nationally severe COVID-19, including pediatric inflammatory multisystem syndrome (PIMS), in hospitalized children. METHODS: An ongoing, prospective, national surveillance was conducted from March 2020 through March 2021, at 20 hospitals treating children <18 years across Israel (~75% of Israeli hospitals). RESULTS: Overall, 1007 cases (439 outpatients and 568 hospitalized) identified represent 0.35% of pediatric COVID-19 nationwide (n = 291 628). Of hospitalized cases, 464 (82%), 48 (8%), and 56 (10%) had mild, moderate/severe, and PIMS disease, respectively. The mean +/- SD age was 5.6 +/- 6.4 years. In mild, moderate/severe, and PIMS disease, 55%, 23%, and 4% of patients were <1 year old, respectively. Obesity was reported in 1%, 4%, and 13% of patients, respectively (P < .001). The most common symptom was fever in 67%, 60%, and 100%, respectively, whereas respiratory symptoms were documented in 33%, 41%, and 38% of patients, respectively. Lymphopenia was recorded in 25%, 60%, and 86% of cases, respectively. PIMS diagnosis was mainly serology-based (in 59%). Gastrointestinal symptoms, cardiovascular involvement, rash, and conjunctivitis were noted in 82%, 61%, 57%, and 34% of PIMS episodes, respectively. Elevated C-reactive protein (100%), ferritin, troponin, D-dimer, low albumin, and thrombocytopenia were common in PIMS. Echocardiography revealed pathological findings in 33% of patients. PIMS mainstay treatment included corticosteroids (77%) and intravenous immunoglobulin (53%). No mortality was recorded. CONCLUSIONS: At a national level, pediatric COVID-19 is mild, even in hospitalized cases, with only a third presenting with respiratory involvement. PIMS is rare, but necessitates a high index of suspicion, and with suitable treatment prognosis is favorable. |*COVID-19[MESH] |Child[MESH] |Child, Hospitalized[MESH] |Child, Preschool[MESH] |Humans[MESH] |Infant[MESH] |Israel/epidemiology[MESH] |Prospective Studies[MESH] |SARS-CoV-2[MESH]COVID-19 in a Subset of Hospitalized Children in Israel (epmc).pdf DeepDyve Pubget Overpricing