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10.1186/s12985-021-01594-0 http://scihub22266oqcxt.onion/10.1186/s12985-021-01594-0 34127006!8200793!34127006     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Virol+J 2021 ; 18 (1): 127 Nephropedia Template TP {{tp|p=34127006|t=2021. Influenza co-infection associated with severity and mortality in COVID-19 patients |pdf=|usr=}}{{34127006}} gab.com Text Influenza co-infection associated with severity and mortality in COVID-19 patients JO: Virol J http://www.kidney.de/pget.php?&tw=1&pmid=34127006 #FOAvip BACKGROUND: In COVID-19 patients, undetected co-infections may have severe clinical implications associated with increased hospitalization, varied treatment approaches and mortality. Therefore, we investigated the implications of viral and bacterial co-infection in COVID-19 clinical outcomes. METHODS: Nasopharyngeal samples were obtained from 48 COVID-19 patients (29% ICU and 71% non-ICU) and screened for the presence of 24 respiratory pathogens using six multiplex PCR panels. RESULTS: We found evidence of co-infection in 34 COVID-19 patients (71%). Influenza A H1N1 (n = 17), Chlamydia pneumoniae (n = 13) and human adenovirus (n = 10) were the most commonly detected pathogens. Viral co-infection was associated with increased ICU admission (r = 0.1) and higher mortality (OR 1.78, CI = 0.38-8.28) compared to bacterial co-infections (OR 0.44, CI = 0.08-2.45). Two thirds of COVID-19 critically ill patients who died, had a co-infection; and Influenza A H1N1 was the only pathogen for which a direct relationship with mortality was seen (r = 0.2). CONCLUSIONS: Our study highlights the importance of screening for co-infecting viruses in COVID-19 patients, that could be the leading cause of disease severity and death. Given the high prevalence of Influenza co-infection in our study, increased coverage of flu vaccination is encouraged to mitigate the transmission of influenza virus during the on-going COVID-19 pandemic and reduce the risk of severe outcome and mortality. Twit Text FOAVip Influenza co-infection associated with severity and mortality in COVID-19 patients ????Virol J http://www.kidney.de/pget.php?&tw=1&pmid=34127006 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34127006 #FOAvip English Wikipedia <ref>{{Cite pmid|34127006}}</ref> Influenza co-infection associated with severity and mortality in COVID-19 patients #MMPMID34127006 Alosaimi B; Naeem A; Hamed ME; Alkadi HS; Alanazi T; Al Rehily SS; Almutairi AZ; Zafar A Virol J 2021[Jun]; 18 (1): 127 PMID34127006show ga BACKGROUND: In COVID-19 patients, undetected co-infections may have severe clinical implications associated with increased hospitalization, varied treatment approaches and mortality. Therefore, we investigated the implications of viral and bacterial co-infection in COVID-19 clinical outcomes. METHODS: Nasopharyngeal samples were obtained from 48 COVID-19 patients (29% ICU and 71% non-ICU) and screened for the presence of 24 respiratory pathogens using six multiplex PCR panels. RESULTS: We found evidence of co-infection in 34 COVID-19 patients (71%). Influenza A H1N1 (n = 17), Chlamydia pneumoniae (n = 13) and human adenovirus (n = 10) were the most commonly detected pathogens. Viral co-infection was associated with increased ICU admission (r = 0.1) and higher mortality (OR 1.78, CI = 0.38-8.28) compared to bacterial co-infections (OR 0.44, CI = 0.08-2.45). Two thirds of COVID-19 critically ill patients who died, had a co-infection; and Influenza A H1N1 was the only pathogen for which a direct relationship with mortality was seen (r = 0.2). CONCLUSIONS: Our study highlights the importance of screening for co-infecting viruses in COVID-19 patients, that could be the leading cause of disease severity and death. Given the high prevalence of Influenza co-infection in our study, increased coverage of flu vaccination is encouraged to mitigate the transmission of influenza virus during the on-going COVID-19 pandemic and reduce the risk of severe outcome and mortality. |Adult[MESH] |Aged[MESH] |Bacterial Infections/epidemiology/mortality/pathology[MESH] |COVID-19/epidemiology/*mortality/pathology[MESH] |Coinfection/epidemiology/*mortality/pathology[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Influenza A Virus, H1N1 Subtype/isolation & purification[MESH] |Influenza, Human/epidemiology/*mortality/pathology[MESH] |Intensive Care Units[MESH] |Male[MESH] |Middle Aged[MESH] |Nasopharynx/microbiology/virology[MESH] |Prevalence[MESH] |SARS-CoV-2/isolation & purification[MESH]Influenza co-infection associated with severity and mortality in COVID(epmc).pdf DeepDyve Pubget Overpricing