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10.1002/cyto.a.24470 http://scihub22266oqcxt.onion/10.1002/cyto.a.24470 34125495!8426831!34125495     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cytometry+A 2023 ; 103 (2): 127-135 Nephropedia Template TP {{tp|p=34125495|t=2023. Impact of age and gender on lymphocyte subset counts in patients with COVID-19 |pdf=|usr=}}{{34125495}} gab.com Text Impact of age and gender on lymphocyte subset counts in patients with COVID-19 JO: Cytometry A http://www.kidney.de/pget.php?&tw=1&pmid=34125495 #FOAvip In symptomatic patients with acute Coronavirus disease 2019 (COVID-19), lymphocytopenia is one of the most prominent laboratory findings. However, to date age and gender have not been considered in assessment of COVID-19-related cell count alterations. In this study, the impact of COVID-19 as well as age and gender on a large variety of lymphocyte subsets was analyzed in 33 COVID-19 patients and compared with cell counts in 50 healthy humans. We confirm that cell counts of total lymphocytes, B, NK, cytotoxic and helper T cells are reduced in patients with severe COVID-19, and this tendency was observed in patients with moderate COVID-19. Decreased cell counts were also found in all subsets of these cell types, except for CD4+ and CD8+ effector memory RA+ (EMRA) and terminal effector CD8+ cells. In multivariate analysis however, we show that in addition to COVID-19, there is an age-dependent reduction of total, central memory (CM), and early CD8+ cell subsets, as well as naive, CM, and regulatory CD4+ cell subsets. Remarkably, reduced naive CD8+ cell counts could be attributed to age alone, and not to COVID-19. By contrast, decreases in other subsets could be largely attributed to COVID-19, and only partly to age. In addition to COVID-19, male gender was a major factor influencing lower counts of CD3+ and CD4+ lymphocyte numbers. Our study confirms that cell counts of lymphocytes and their subsets are reduced in patients with COVID-19, but that age and gender must be considered when interpreting the altered cell counts. Twit Text FOAVip Impact of age and gender on lymphocyte subset counts in patients with COVID-19 ????Cytometry A http://www.kidney.de/pget.php?&tw=1&pmid=34125495 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34125495 #FOAvip English Wikipedia <ref>{{Cite pmid|34125495}}</ref> Impact of age and gender on lymphocyte subset counts in patients with COVID-19 #MMPMID34125495 Lohr P; Schiele S; Arndt TT; Grutzner S; Claus R; Rommele C; Muller G; Schmid C; Dennehy KM; Rank A Cytometry A 2023[Feb]; 103 (2): 127-135 PMID34125495show ga In symptomatic patients with acute Coronavirus disease 2019 (COVID-19), lymphocytopenia is one of the most prominent laboratory findings. However, to date age and gender have not been considered in assessment of COVID-19-related cell count alterations. In this study, the impact of COVID-19 as well as age and gender on a large variety of lymphocyte subsets was analyzed in 33 COVID-19 patients and compared with cell counts in 50 healthy humans. We confirm that cell counts of total lymphocytes, B, NK, cytotoxic and helper T cells are reduced in patients with severe COVID-19, and this tendency was observed in patients with moderate COVID-19. Decreased cell counts were also found in all subsets of these cell types, except for CD4+ and CD8+ effector memory RA+ (EMRA) and terminal effector CD8+ cells. In multivariate analysis however, we show that in addition to COVID-19, there is an age-dependent reduction of total, central memory (CM), and early CD8+ cell subsets, as well as naive, CM, and regulatory CD4+ cell subsets. Remarkably, reduced naive CD8+ cell counts could be attributed to age alone, and not to COVID-19. By contrast, decreases in other subsets could be largely attributed to COVID-19, and only partly to age. In addition to COVID-19, male gender was a major factor influencing lower counts of CD3+ and CD4+ lymphocyte numbers. Our study confirms that cell counts of lymphocytes and their subsets are reduced in patients with COVID-19, but that age and gender must be considered when interpreting the altered cell counts. |*COVID-19[MESH] |CD4-Positive T-Lymphocytes[MESH] |CD8-Positive T-Lymphocytes[MESH] |Humans[MESH] |Lymphocyte Count[MESH] |Lymphocyte Subsets[MESH] |Male[MESH]Impact of age and gender on lymphocyte subset counts in patients with (epmc).pdf DeepDyve Pubget Overpricing