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10.1002/jmv.27132 http://scihub22266oqcxt.onion/10.1002/jmv.27132 34125455!8427004!34125455     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2021 ; 93 (10): 5729-5741 Nephropedia Template TP {{tp|p=34125455|t=2021. Molecular biology of the SARs-CoV-2 spike protein: A review of current knowledge |pdf=|usr=}}{{34125455}} gab.com Text Molecular biology of the SARs-CoV-2 spike protein: A review of current knowledge JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=34125455 #FOAvip The global coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an unprecedented worldwide public health emergency. Despite the concerted efforts of the scientific field, by April 25, 2021, SARS-CoV-2 had spread to over 192 countries/regions, causing more than 146 million confirmed cases including 31 million deaths. For now, an established treatment for patients with COVID-19 remains unavailable. The key to tackling this pandemic is to understand the mechanisms underlying its infectivity and pathogenicity. As a predominant focus, the coronavirus spike (S) protein is the key determinant of host range, infectivity, and pathogenesis. Thereby comprehensive understanding of the sophisticated structure of SARS-CoV-2 S protein may provide insights into possible intervention strategies to fight this ongoing global pandemic. Herein, we summarize the current knowledge of the molecular structural and functional features of SARS-CoV-2 S protein as well as recent updates on the cell entry mechanism of the SARS-CoV-2, paving the way for exploring more structure-guided strategies against SARS-CoV-2. Twit Text FOAVip Molecular biology of the SARs-CoV-2 spike protein: A review of current knowledge ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=34125455 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34125455 #FOAvip English Wikipedia <ref>{{Cite pmid|34125455}}</ref> Molecular biology of the SARs-CoV-2 spike protein: A review of current knowledge #MMPMID34125455 Zhu C; He G; Yin Q; Zeng L; Ye X; Shi Y; Xu W J Med Virol 2021[Oct]; 93 (10): 5729-5741 PMID34125455show ga The global coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an unprecedented worldwide public health emergency. Despite the concerted efforts of the scientific field, by April 25, 2021, SARS-CoV-2 had spread to over 192 countries/regions, causing more than 146 million confirmed cases including 31 million deaths. For now, an established treatment for patients with COVID-19 remains unavailable. The key to tackling this pandemic is to understand the mechanisms underlying its infectivity and pathogenicity. As a predominant focus, the coronavirus spike (S) protein is the key determinant of host range, infectivity, and pathogenesis. Thereby comprehensive understanding of the sophisticated structure of SARS-CoV-2 S protein may provide insights into possible intervention strategies to fight this ongoing global pandemic. Herein, we summarize the current knowledge of the molecular structural and functional features of SARS-CoV-2 S protein as well as recent updates on the cell entry mechanism of the SARS-CoV-2, paving the way for exploring more structure-guided strategies against SARS-CoV-2. |COVID-19/virology[MESH] |Host Specificity[MESH] |Humans[MESH] |Mutation[MESH] |Protein Conformation[MESH] |Protein Subunits[MESH] |Receptors, Virus/genetics/metabolism[MESH] |SARS-CoV-2/classification/pathogenicity/*physiology[MESH] |Spike Glycoprotein, Coronavirus/*chemistry/genetics/*metabolism[MESH]Molecular biology of the SARs-CoV-2 spike protein: A review of current(epmc).pdf DeepDyve Pubget Overpricing